Role of coatings and materials of external fixation pins on the rates of pin tract infection:A systematic review and meta-analysis  

作　　者：Cristhopher Stoffel Bruno Eltz Mauro Jose Salles 

机构地区：[1]Department of Orthopedic Surgery,Instituto de Ortopedia e Traumatologia do Rio Grande do Sul,Passo Fundo 99010110,Rio Grande do Sul,Brazil [2]Department of Orthopedic Surgery,Hospital São Francisco,Concordia 89700-000,Santa Catarina,Brazil [3]Musculoskeletal Infection Group,Internal Medicine Department,Santa Casa de Sao Paulo School of Medical Sciences,Sao Paulo 01221-020,Brazil [4]Musculoskeletal Infection Group,Division of Infectious Diseases,Escola Paulista de Medicina,Universidade Federal de Sao Paulo,Sao Paulo 01221-020,Brazil

出　　处：《World Journal of Orthopedics》2021年第11期920-930,共11页世界骨科杂志（英文版）

摘　　要：BACKGROUND Infection at the pin tract is a frequent and feared complication of external fixators(EF).The type of pin material and coatings have been regarded as possibly influencing infection rates.Over the last 20 years,few prospective clinical studies and systematic reviews addressed the role of coated pins on the rate of pin site infection in human clinical studies.AIM To assess the EF literature over the past 20 years on the clinical benefits of pins manufactured from varied materials and coating systems and their possible role in pin tract infection rates.METHODS We performed a systematic review according to the PRISMA and PICOS guidelines using four scientific platforms:PubMed,LiLacs,SciELO,and Cochrane.We searched the literature for related publications over the past 20 years.RESULTS A literature search yielded 29 articles,among which seven met the inclusion criteria.These studies compared stainless-steel pins and pins coated with hydroxyapatite(HA),titanium and silver.The pin tract infection definitions were arbitrary and not standardized among studies.Most studies included a low number of patients in the analysis and used a short follow-up time.Three metaanalyses were carried out,comparing stainless steel vs silver pins,stainless steel vs HA-coated pins,and titanium vs HA-coated pins.None of this analysis resulted in statistically significant differences in pin tract infection rates.CONCLUSION Currently,no clinical evidence supports the advantage of EF pins manufactured with materials other than stainless steel or coated over uncoated pins in reducing the rates of pin tract infections.A standardized definition of pin tract infection in external fixation is still lacking.

关 键 词：External fixator Pin tract infection Stainless steel pin Coated pin Coating systems Pin site infection 

分 类 号：R318.08[医药卫生—生物医学工程]