溃疡性结肠炎合并下肢静脉血栓形成患者的抗凝实践  

Anticoagulant practice in a patient with ulcerative colitis and lower extremity venous thrombosis

作　　者：高立娜[1] 张新茹[1] 宋扬[1] 张静[1] GAO Li-na;ZHANG Xin-ru;SONG Yang;ZHANG Jing(Department of Pharmacy,the Second Hospital of Jilin University,Changchun 130041,China)

机构地区：[1]吉林大学第二医院药学部,吉林长春130041

出　　处：《中国药物应用与监测》2021年第5期305-307,共3页Chinese Journal of Drug Application and Monitoring

摘　　要：1例15岁男性患者因近期无明显诱因腹泻、便中鲜血、皮肤苍白、乏力收入我院。入院后,血管彩超提示双侧下肢静脉血栓(急性或亚急性期);腹部彩超提示结肠炎症改变,散在小溃疡斑。临床药师协助医生为患者制定个体化的抗凝治疗方案,在院期间对患者进行药学监护及用药指导,患者出院时已无黏液脓血便症状。出院后随访3个月,患者无异常出血发生,复查彩超见下肢血栓部分再通,预后良好。A 15-year-old male patient was admitted to the hospital due to diarrhea,bloody stools,skin pallor,and fatigue in recent period.After admission,the vascular color doppler ultrasound showed venous thrombosis(acute or subacute stage)in both lower limbs.And abdominal color doppler ultrasound showed colonic infl ammation with scattered small ulcer spots.Clinical pharmacist assisted doctors to make individual anticoagulant regimen and provided pharmaceutical care and medication guidance to the patient during the treatment.The patient was discharged with no mucus and blood in the stool.After 3 months of follow-up,he didn't develop abnormal bleeding and the color doppler ultrasound showed his lower limb thrombosis was partially recanalization,the prognosis was good.

关 键 词：溃疡性结肠炎 儿童 抗凝 达肝素 利伐沙班 药学监护 

分 类 号：R969.4[医药卫生—药理学]