沙棘干乳剂、复方消化酶联合应用治疗功能性消化不良临床效果分析  

Clinical effect of sea buckthorn dry emulsion combined with compound digestive enzyme on functional dyspepsia

作　　者：黄丽红 屈元婷 张珊旗 HUANG Li-hong(Hongqi Hospital, Mudanjiang Medical University, Mudanjiang 157011, China)

机构地区：[1]牡丹江医学院附属红旗医院,黑龙江牡丹江157011

出　　处：《牡丹江医学院学报》2021年第6期50-52,86,共4页Journal of Mudanjiang Medical University

摘　　要：目的本文为了探讨沙棘干乳剂、复方消化酶联合应用治疗功能性消化不良临床效果。方法选取2019年1月至2021年7月期间治疗的100例功能性消化不良患者作为本次研究对象,采用随机数表法分为对照组和观察组,各50例。对照组给予沙棘干乳剂治疗,观察组给予沙棘干乳剂、复方消化酶胶囊联合应用。比较两组临床疗效、胃动力及不良反应。结果观察组治疗后腹痛、早饱、嗳气、腹胀症状评分分别为:(0.70±0.19)分、(0.67±0.28)分、(0.73±0.33)分和(0.91±0.30)分;对照组治疗后腹痛、早饱、嗳气、腹胀症状评分分别为:(0.95±0.24)分、(0.79±0.41)分、(0.81±0.33)分和(0.99±0.26)分,两组治疗后症状评分较治疗前明显降低(P<0.05);观察组治疗总有效率高于对照组(P<0.05);观察组治疗后胃、肠排空率明显高于对照组(P<0.05);观察组不良反应发生率与对照组无显著差异(P>0.05)。结论沙棘干乳剂、复方消化酶胶囊联合应用治疗功能性消化不良有明显疗效,同时有效增强胃动力,未增加不良反应,具有较好安全性。To investigate the clinical effect of combined application of sea buckthorn dry emulsion and compound digestive enzyme in the treatment of functional dyspepsia.Methods 100 patients with functional dyspepsia who were treated from January 2019 to July 2021 were selected as the subjects of this study,and were divided into control group and observation group by random number table method,with 50 patients in each group.The control group was treated with dry sea-buckthorn emulsion,and the observation group was treated with dry sea-buckthorn emulsion and compound digestive enzyme capsule.The clinical efficacy,gastric motility and adverse reactions of the two groups were compared.Results Symptom scores of abdominal pain,early satiety,belching and abdominal distension were(0.70±0.19)points,(0.67±0.28)points,(0.73±0.33)points and(0.91±0.30)points in the observation group after treatment,respectively.The symptom scores of abdominal pain,early satiety,belching and abdominal distension in the control group were(0.95±0.24),(0.79±0.41),(0.81±0.33)and(0.99±0.26),respectively.The symptom scores of the two groups after treatment were significantly lower than those before treatment(P<0.05).Symptom score of the two groups after treatment:abdominal pain symptom score of the observation group was significantly lower than that of the control group(P<0.05),abdominal distension score of the observation group was significantly lower than that of the control group(P<0.05),belching score of the observation group was significantly lower than that of the control group(P<0.05),and early satiety score had no significant difference between the two groups(P>0.05).After treatment,the total effective rate of observation group was higher than that of the control group(P<0.05);The gastric and intestinal empty rates in the observation group were significantly higher than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P>0.05).Conclu

关 键 词：功能性消化不良 沙棘干乳剂 复方消化酶 胃动力 

分 类 号：R285.5[医药卫生—中药学]