243例心血管疾病患者使用注射用尼可地尔的合理性评价  

Rational Evaluation of Nicordil Injection in 243 Patients with Cardiovascular Disease

作　　者：徐胜 田霞[1] 唐慧 XU Sheng;TIAN Xia;TANG Hui(Department of Pharmacy,Changshu No.1 People's Hospital,Changshu Jiangsu 215500,China)

机构地区：[1]常熟市第一人民医院药剂科,江苏常熟215500

出　　处：《抗感染药学》2021年第8期1102-1106,共5页Anti-infection Pharmacy

摘　　要：目的:评价心血管疾病住院患者注射用尼可地尔临床使用情况,为规范其合理使用提供参考。方法:通过医院信息系统(HIS)抽取2019年1月—2020年6月每月11—20日出院的使用注射用尼可地尔的住院患者病历243份,评价注射用尼可地尔临床使用的适应证、用法用量、用药疗程、联合用药、用药禁忌和不良反应等方面的合理性。结果:243例心血管疾病住院患者中临床使用注射用尼可地尔完全合理者44例(占18.11%),适应证不适宜者108例(占44.44%),用药的疗程偏长者125例(占51.44%),联合用药不适宜者26例(占10.70%),存在用药禁忌者8例(占3.29%),以及用药期间出现可疑不良反应患者45例(占18.52%)。结论:心血管疾病住院患者注射用尼可地尔的使用存在过度用药现象,临床应严格控制注射用尼可地尔的使用指征,规范其用法用量、用药疗程与用药禁忌,避免其经验性过度用药,以确保患者用药的安全性与有效性。Objective: To evaluate the clinical medications of nicorandil for injection in in-patients with cardiovascular diseases and to provide reference for regulating its rational usage. Methods: The hospital information system(HIS)was used to select 243 patients who were discharged on 11 th to 20 th of each month from January 2019 to June 2020 for retrospective analysis, and the rationality of clinical medications of nicorandil for injection in terms of indication, usage and dosage, medication course, drug combination, drug contraindication and adverse drug reactions were evaluated. Results: In 243 inpatients with cardiovascular diseases, 44 cases(18.11%) were completely reasonable in the use of nicorandil for injection, 108 cases(44.44%) were unsuitable, 125 cases(51.44%) were older in the course of medication, and26 cases(10.70%) were unsuitable in combination with nicorandil for injection. There were 8 cases with contraindication(3.29%), and 45 cases with suspected adverse reactions(18.52%) during medication. Conclusion: Overuse of nicardil for injection in inpatients with cardiovascular diseases is a phenomenon. Clinically, indications of nicardil for injection should be strictly controlled, usage and dosage, medication course and contraband of nicorandil should be regulated, and empirical overuse should be avoided so as to ensure the safety and effectiveness of medication.

关 键 词：心血管疾病 尼可地尔 用药合理性 合理性评价 合理用药 

分 类 号：R969.3[医药卫生—药理学]