基于光梭成像的新型加速技术在颅脑MRI中的应用价值研究  

Application value of new accelerating technology based on constellation shuttling imaging in brain MRI

作　　者：张雪坤 李彦[1] 严福华[1] 赵洪飞 宋琦[1] ZHANG Xuekun;LI Yan;YAN Fuhua;ZHAO Hongfei;SONG Qi(Department of Radiology,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属瑞金医院放射科,上海200025

出　　处：《诊断学理论与实践》2021年第4期378-383,共6页Journal of Diagnostics Concepts & Practice

基　　金：上海市“科技创新行动计划”产学研医合作领域项目(18DZ1930103)。

摘　　要：目的:评估基于光梭成像(constellation shuttling imaging,uCS)技术加速的颅脑MRI图像质量及扫描时间,为其在临床常规化应用提供依据。方法:20名志愿者每人接受2次颅脑MRI扫描,包括快速自旋回波轴位T1加权成像(T1-weighted imaging,T1WI)、T2-液体抑制反转恢复序列(fluid attenuated inversion recovery sequence,FLAIR)、矢状位T1WI及梯度回波矢状位3D-T1WI序列扫描,分别采用并行采集技术(即常规扫描)和uCS加速技术,记录并比较扫描时间。采用主观(Likert 5级评分法,内容包括图像伪影及整体质量)与客观(定量测定图像信噪比)相结合的方法,对各序列采集的图像质量进行综合评价。结果:基于uCS技术加速后的颅脑MRI扫描时间均比常规扫描时间缩短约26.3%(542 s比735 s),其中3D序列时间缩短尤为明显,达39.0%。在图像整体质量及伪影评估方面,各项uCS加速序列与常规扫描序列之间差异均无统计学意义(P>0.05)。在信噪比方面,uCS轴位及矢状位T1WI序列的信噪比显著高于常规扫描轴位及矢状位T1WI序列(P<0.05)。uCS加速的FLAIR及3D-T1WI与常规扫描序列相比,信噪比差异没有统计学意义(P>0.05)。结论:与常规MRI序列扫描相比,uCS技术可以显著缩短脑部MRI的图像采集时长,同时能保证图像质量。Objective:To evaluate the image quality of brain MRI sequences accelerated by constellation shuttling imaging(uCS)to provide a basis for clinical application.Methods:Twenty volunteers underwent brain MRI scanning(TSE axial T1WI,T2-FLAIR,sagittal T1WI and GRE sagittal 3D-T1WI)twice using parallel imaging(routine scanning)and corresponding uCS accelerated acquisition.The evaluation of images in each sequence was conducted through combin-ing the subjective(Likert five-point scale method,image artifact and overall quality)and objective(signal-to-noise ratio measurement)methods.Results:The scanning time of using uCS in each MRI sequence was shorter than that of conventional scanning.The total scanning time of uCS in each volunteer was 542 s,while that of conventional scanning was 735 s,which decreased 26.3%.The scanning time of 3D sequence was nearly reduced 39%.There is no statistically difference between uCS and conventional sequence in subjective evaluation(overall image quality and image artifact degree).The SNR of uCS axial T1WI and sagittal T1WI sequences was significantly higher than those of conventional axial T1WI and sagittal T1WI sequences(P<0.05).In addition,there was no difference between uCS and conventional scanning in SNR of FLAIR and 3D-T1WI sequences.Conclusions:Compared with conventional scanning,uCS can significantly accelerate the acquisition of brain MR images without loss of image quality.

关 键 词：磁共振成像 光梭成像 压缩感知 图像质量 

分 类 号：R445.2[医药卫生—影像医学与核医学]