Clerodane-type Diterpene Glycosides from Dicranopteris pedata  

作　　者：Bei‑Bei Gao Yu‑Fei Ou Qin‑Feng Zhu Zhi‑Ping Zhou Zhen‑Tao Deng Meng Li Qin‑Shi Zhao 

机构地区：[1]Key Laboratory of Medicinal Chemistry for Natural Resource,Ministry of Education,School of Chemical Science and Technology,Yunnan University,Yunnan,650091 Kunming,People’s Republic of China [2]State Key Laboratory of Phytochemistry and Plant Resources in West China and Yunnan Key Laboratory of Natural Medicinal Chemistry,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China [3]College of Pharmacy,Guizhou Medical University,Guian New Area,Guizhou 550025,China

出　　处：《Natural Products and Bioprospecting》2021年第5期557-564,共8页应用天然产物（英文）

摘　　要：Three new clerodane-type diterpene glycosides,(5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1→4)-α-l-rhamnopyranosyl]cleroda-3,13(16),14-diene(1),(5R,6S,8R,9S,10R,13S)-6-O-[β-d-glucopyranosyl-(1→4)-α-l-rhamnopyranosyl]-2-ox-oneocleroda-3,13-dien-15-ol(2),(5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1→4)-α-l-rhamnopyranosyl]-(13E)-2-oxoneocleroda-3,14-dien-13-ol(3),together with two known compounds 4 and 5 were isolated from Dicranopteris pedata.The structures of these compounds were elucidated by detailed spectroscopic analysis,and the absolute configuration of compound 2 was determined by ECD calculations.In addition,compound 1 exhibited weak inhibitory activities against SMMC-7721,MCF-7 and SW480.

关 键 词：Dicranopteris pedata Clerodane-type diterpene glycosides ECD 

分 类 号：Q50[生物学—生物化学]