2型糖尿病与冠状动脉钙化及心脑血管事件的关系  

Relationship between Type 2 Diabetes Mellitus and Coronary Artery Calcification and Cardiovascular and Cerebrovascular Events

作　　者：肖冬平[1] 范剑峰[1] 郑春华[1] 高招波[1] XIAO Dong-ping;FAN Jian-feng;ZHENG Chun-hua;GAO Zhao-bo(Nanchang First Hospital,Jiangxi Nanchang 330000)

机构地区：[1]南昌市第一医院,江西南昌330000

出　　处：《深圳中西医结合杂志》2021年第17期18-20,共3页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基　　金：江西省卫生计生委科技计划项目资助课题(20160726)。

摘　　要：目的:探讨2型糖尿病(T2DM)与冠状动脉钙化及心脑血管事件的关系。方法:选择2015年8月至2018年5月就诊于南昌市第一医院的100例T2DM患者为研究对象,均接受64层螺旋计算机断层扫描(CT)检查。分析T2DM患者冠状动脉钙化情况、心脑血管事件发生情况,比较不同冠状动脉钙化程度患者心脑血管事件发生情况。结果:100例T2DM患者中出现钙化病灶67例(67.00%),其中轻度钙化42例(42.00%),中度钙化15例(15.00%),重度钙化10例(10.00%),发生心脑血管事件19例(19.00%);随冠状动脉钙化程度加重,心脑血管事件发生率逐渐增高,差异具有统计学意义(P<0.05);Logistic回归分析显示,T2DM、钙化积分是心脑血管事件发生的独立危险因素。结论:T2DM易发生冠状动脉钙化、心脑血管事件,T2DM、钙化积分是心脑血管事件发生的独立危险因素。Objective To investigate the relationship between type 2 diabetes mellitus(T2DM)and coronary artery calcification and cardiovascular and cerebrovascular events.Methods A total of 100 T2DM patients admitted to The First Hospital of Nanchang city from August 2015 to May 2018 were selected as subjects.All patients underwent 64-slice spiral computed tomography(CT).The incidence of coronary artery calcification and cardiovascular and cerebrovascular events in T2DM patients was analyzed,and the incidence of cardiovascular and cerebrovascular events in patients with different degrees of coronary artery calcification was compared.Results Among 100 T2DM patients,67 cases(67.00%)had calcification,including 42 cases(42.00%)with mild calcification,15 cases(15.00%)with moderate calcification,10 cases(10.00%)with severe calcification,19 cases(19.00%)with cardiovascular and cerebrovascular events.With the aggravation of coronary artery calcification,the incidence of cardiovascular and cerebrovascular events gradually increased,and the difference was statistically significant(P<0.05).Logistic regression analysis showed that T2DM and calcification score were independent risk factors for cardiovascular and cerebrovascular events.Conclusion T2DM is prone to coronary artery calcification and cardiovascular and cerebrovascular events,and T2DM and calcification score are independent risk factors for cardiovascular and cerebrovascular events.

关 键 词：2型糖尿病 冠状动脉钙化 心脑血管事件 

分 类 号：R587.1[医药卫生—内分泌]