CT引导下半月神经节射频热凝术与三氧注射治疗三叉神经痛的疗效比较  

Comparison of the efficacy of CT-guided percutaneous radiofrequency thermocoagulation and ozone injection of the gasserian ganglion in the treatment of trigeminal neuralgia

作　　者：李彤 钱晓焱[4] 郑蓉 胡桂莲 白清丽[3] 李芝兰 张建峰[4] 安建雄 LI Tong;QIAN Xiaoyan;ZHENG Rong;HU Guilian;BAI Qingli;LI Zhilan;ZHANG Jianfeng;AN Jianxiong(Department of Pain Medicine,The First People's Hospital of Lanzhou,Lanzhou 730050,China;Department of Pain Medicine,Maternal and Child Health Hospital of Lanzhou,Lanzhou 730030,China;School of Public Health,Lanzhou University,Lanzhou 730000,China;Department of Anesthesiology,Pain&Sleep Medicine,Aviation General Hospital of China Medical University,Beijing 100012,China)

机构地区：[1]兰州市第一人民医院疼痛科,兰州730050 [2]兰州市妇幼保健院疼痛科,兰州730000 [3]兰州大学公共卫生学院,兰州730000 [4]中国医科大学航空总医院麻醉/疼痛与睡眠医学中心,北京100012

出　　处：《中国疼痛医学杂志》2021年第10期744-749,共6页Chinese Journal of Pain Medicine

基　　金：首都医学发展基金(202036101);兰州市人才创新创业项目(2020-RC-78);甘肃省自然科学基金(21JR1RA189)。

摘　　要：目的:比较CT引导下半月神经节射频热凝术与三氧注射治疗三叉神经痛的疗效。方法:收集2014至2020年因三叉神经痛接受治疗的病人诊疗信息,按手术方法分为经皮射频热凝术(percutaneous radiofrequency thermocoagulation,PRT)组14例和三氧注射治疗(ozone therapy,OT)组13例;并进行随访。采用视觉模拟评分法(visual analogue scale,VAS)评分及巴罗神经学研究所(Barrow neurological institute,BNI)疼痛评分,评估病人疼痛(pain)和麻木(numbness)程度。结果:两组治疗前VAS,BNI(P)和BNI(N)评分差异均无统计学意义。治疗后1周VAS和BNI(P)评分均降低;但OT组高于PRT组。治疗后BNI(N)评分OT组均低于PRT组。随访期间PRT组2例疼痛复发,病人均有麻木症状;OT组5例病人偶发轻微疼痛,均无麻木症状。结论:OT和PRT均可缓解三叉神经痛,OT缓解疼痛的效果略低于PRT,但OT组的病人术后麻木程度低于PRT组。Objective:To compare the effects of percutaneous radiofrequency thermocoagulation(PRT)and ozone therapy(OT)in the treatment of trigeminal neuralgia(TN).Methods:We collected the clinical information and outcome measurements of patients with TN from 2014 to 2020.Patients were divided into two groups according to different treatment approaches:PRT group(n=14)and OT group(n=13).The visual analogue scale(VAS)and Barrow neurological institute(BNI)were used to measure the levels of pain and numbness in patients with TN.Results:There were no significant differences in VAS scores,BNI(P)and BNI(N)scores between two groups at the baseline.Compared with pre-treatment,VAS score and BNI(P)score decreased in both groups 1 week after treatment.However,VAS score and BNI(P)score in OT group were higher than those in PRT group.After treatment,BNI(N)scores in OT group were lower than those in PRT group.Five patientsin OT group had occasional mild pain,and no patients had numbness symptoms.In the PRT group,2 patients had pain,and all patients had numbness symptoms.Conclusion:Both treatment methods could alleviate TN.The short-term analgesic effect of OT on pain was not as good as PRT,However,the degree of facial numbness of patients in OT group was significanted lower than that in PRT group.

关 键 词：三叉神经痛 射频热凝术 三氧注射治疗 半月神经节 

分 类 号：R651.3[医药卫生—外科学]