野生型转甲状腺素蛋白心脏淀粉样变一例  

A case of wild-type transthyretin cardiac amyloidosis

作　　者：秦莹 孙筱璐[1] 王东[1] 蒋文[1] 王红月[2] 孙晓昕[3] 方纬[3] 李剑[4] 田庄[5] 宋雷[1] 康连鸣[1] Qin Ying;Sun Xiaolu;Wang Dong;Jiang Wen;Wang Hongyue;Sun Xiaoxin;Fang Wei;Li Jian;Tian Zhuang;Song Lei;Kang Lianming(Department of Cardiomyopathy,Fuwai Hospital,National Cen ter for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China;Department of Pathology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China;Department of Nuclear Medicine,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China;Department of Hematology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;Department of Cardiology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,国家心血管病中心,阜外医院心肌病病区,100037 [2]中国医学科学院,北京协和医学院,国家心血管病中心,阜外医院病理科,100037 [3]中国医学科学院,北京协和医学院,国家心血管病中心,阜外医院核医学科,100037 [4]中国医学科学院,北京协和医学院,北京协和医院血液科,100730 [5]中国医学科学院,北京协和医学院,北京协和医院心内科,100730

出　　处：《中华心血管病杂志》2021年第10期1023-1026,共4页Chinese Journal of Cardiology

摘　　要：转甲状腺素蛋白心脏淀粉样变(ATTR-CA)是由转甲状腺素蛋白发生异常解离并聚集在心肌间质所导致,其中野生型(ATTRwt)为无TTR基因突变者。由于该病临床表现缺乏特异性,易被漏诊、误诊。该文报道了1例初诊为肥厚型心肌病最终确诊为ATTRwt患者的诊治过程。

关 键 词：淀粉样变性 心脏 

分 类 号：R541[医药卫生—心血管疾病]