腹主动脉瘤发生机制的研究进展  

Advances in pathogenesis of abdominal aortic aneurysm

作　　者：王鼎 贾龙元 姜波[1,2] 辛世杰 Wang Ding;Jia Longyuan;Jiang Bo;Xin Shijie(Department of Vascular Surgery,The First Hospital of China Medical University,Shenyang 110001,Liaoning,China;Liaoning Provincial Key Laboratory of Etiology and Prevention of Aneurysm Disease,Shenyang 110001,Liaoning,China)

机构地区：[1]中国医科大学附属第一医院血管外科,辽宁沈阳110001 [2]辽宁省动脉瘤疾病病因与防治研究重点实验室,辽宁沈阳110001

出　　处：《血管与腔内血管外科杂志》2021年第6期659-663,共5页Journal of Vascular and Endovascular Surgery

基　　金：国家自然科学基金(81974049)。

摘　　要：随着中国人口进入老龄化阶段,腹主动脉瘤(AAA)的发生率逐年升高,严重威胁着人类的健康。在对AAA患者积极进行诊治的同时,对AAA发生、发展机制的研究亦至关重要,有利于从根本上对其进行诊断与治疗。据临床统计,95%的AAA被诊断为因衰老等原因所致的动脉粥样硬化性AAA。本文将对AAA的发生、发展机制及诊疗进展进行系统性综述。With the aging of Chinese people,the incidence rate of abdominal aortic aneurysms(AAA)increases year by year,posing a serious threat to human health.While making various diagnosis and treatment actively,it is also very important to study the occurrence and development mechanism of AAA,so as to fundamentally diagnose and treat this kind of disease.Clinical statistics showed that about 95%cases of AAA were diagnosed as atherosclerotic AAA caused by aging and other reasons.Therefore,it is of great significance to study the pathogenesis of such aneurysms.This paper will systematically review the occurrence,development mechanism,diagnosis and treatment of AAA.

关 键 词：腹主动脉瘤 发病机制 老龄化 动脉硬化 细胞衰老 

分 类 号：R543[医药卫生—心血管疾病]