Controversial protamine in dealing with acute cardiac tamponade during radiofrequency ablation  

作　　者：Dong-Dong Que Li-Yun Feng Ya-Shu Yang Xu-Dong Song Ping-Zhen Yang 

机构地区：[1]Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease,Zhujiang Hospital,Southern Medical University,Guangzhou,Guangdong 510280,China [2]Sino-Japanese Cooperation Platform for Translational Research in Heart Failure,Zhujiang Hospital,Southern Medical University,Guangzhou,Guangdong 510280,China [3]Laboratory of Heart Center,Zhujiang Hospital,Southern Medical University,Guangzhou,Guangdong 510280,China [4]Department of Cardiology,Heart Center,Zhujiang Hospital,Southern Medical University,Guangzhou,Guangdong 510280,China

出　　处：《Chinese Medical Journal》2021年第20期2503-2505,共3页中华医学杂志（英文版）

基　　金：supported by the Clinical Research Initiation Program of Southern Medical University(No.LC2016ZD022)。

摘　　要：To the Editor:During radiofrequency catheter ablation(RFCA),acute cardiac tamponade is a common but life-threatening occurrence in which rapid blood accumulation in the pericardium cavity compresses the heart and causes the systemic circulation to deteriorate.Emergency percutaneous pericardiocentesis and immediate autologous blood transfusion are necessary.The administration of protamine for incessant bleeding is controversial,for pericardial blood clots may form spontaneously despite the neutralizing effects of heparin and may even necessitate thoracotomy.Our aim is to discuss the necessity and optimum time of protamine administration and to explore the means to prevent blood clot formation.

关 键 词：ACUTE TRANSFUSION dealing 

分 类 号：R542.1[医药卫生—心血管疾病]