宫腔内夫精人工授精妊娠率与注入前向运动精子总数的关系分析  

The relationship between the cycle pregnancy rate of artificial intrauterine insemination and the progressively motile spermatozoa inseminated

作　　者：万富明[1] 林杰[1] 徐庆[1] 郝丽 李丹 Wan Fuming;Lin Jie;Xu Qing(The Maternal and Children’s Health Hospital of Zigong City,Zigong,Sichuan643000)

机构地区：[1]自贡市妇幼保健院,四川自贡643000

出　　处：《基层医学论坛》2021年第32期4604-4605,4608,共3页The Medical Forum

基　　金：自贡市科学技术局2019年市级重点科技计划项目(2019YLSF16)。

摘　　要：目的分析宫腔内夫精人工授精(IUI)周期妊娠率(CPR)与注入前向运动精子总数(NPMSI)的关系,以期获得适宜CPR的NPMSI阈值,为临床治疗提供参考依据。方法回顾性分析2018年6月—2021年1月间165例患者285个IUI周期临床资料,根据NPMSI(1.5~、5.0~、15.0~、30~、45~)分为A、B、C、D及E组,比较各组间CPR差异。结果总CPR为18.59%,5组CPR依次为0.0%,8.2%,22.9%,18.0%和19.2%。C组CPR最高,与B组比较差异有统计学意义(P<0.05);B组、D组、E组间CPR比较,差异无统计学意义(P>0.05),但D、E组CPR明显高于B组。结论NPMSI对IUI妊娠率有一定预测价值,CPR不一定会随着NPMSI的增多而提高,NPMSI 15~30×106是本地区IUI治疗的理想阈值范围。Objective To investigate the relationship between the cycle pregnancy rate(CPR)of artificial intrauterine insemination(IUI)and the number of progressively motile spermatozao inseminated(NPMSI).Method The clinical data in 285 cycles among 165 patients undergoing IUI with the husband’s sperm were retrospectively analyzed.The data was divided into five groups according to NPMSI(1.5~、5.0~、15.0~、30~、45~).The CPRs among different groups were compared.Results The general CPR was 18.59%.The CPR of five groups respectively was 0.0%,8.2%,22.9%,18.0%and 19.2%.The CPR of group C was the highest.There was significant difference(P<0.05)between group C and group B.There was no significant difference(P>0.05)between group B,group D and group E.The CPR of group D or group E is higher than group B.Conclusion NPMSI is a predictive index for IUI CPR.CPR is not all elevated with increased NPMSI.Performing IUI in NPMSI(15~30)×106 can get preferable CPR.

关 键 词：宫腔内人工授精 妊娠率 前向运动精子 相关性 

分 类 号：R321.33[医药卫生—人体解剖和组织胚胎学]