PPR蛋白在植物细胞器组分转录后调控中的作用机制  

The role of PPR proteins in posttranscriptional regulation of organelle components in plants

作　　者：郝媛媛 赵向前 黄福灯[1] 李春寿[1] Yuanyuan Hao;Xiangqian Zhao;Fudeng Huang;Chunshou Li(Institute of Crop and Nuclear Technology Utilization,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China)

机构地区：[1]浙江省农业科学院作物与核技术利用研究所,杭州310021

出　　处：《遗传》2021年第11期1050-1065,共16页Hereditas（Beijing)

基　　金：国家自然科学基金项目(编号:32001524)资助。

摘　　要：PPR(pentatricopeptide repeats)蛋白是陆生植物中最大的蛋白家族之一,是一类RNA结合蛋白,参与细胞器基因的转录后加工过程,对细胞器的生物合成和功能具有深远影响。PPR突变后造成叶绿体光合电子传递链和线粒体呼吸链等进程受损,最终通过影响光合作用或者呼吸作用,造成植株生长发育异常,影响产量、育性、籽粒品质等。近年来,关于该蛋白家族成员参与植物生长发育的报道越来越多,但由于该家族庞大,大部分成员的功能还未被解析。本文系统总结了目前PPR蛋白调控细胞器基因转录后加工的分子机理及对细胞器和植株发育的影响,提出PPR家族还未解决的问题,为深入解析该基因家族的功能及育种应用提供理论基础。Pentatricopeptide repeat(PPR)proteins constitute one of the largest protein families in land plants.They are sequence-specific RNA-binding proteins and play key roles in posttranscriptional processes within organelles.Their combined actions have profound effects on chloroplast photosynthetic electron transport chain and mitochondrial respiratory chain,affecting photosynthesis and respiration respectively,and ultimately on yield,fertility,and grain quality.Over the past decade,much has been learned about the molecular functions of these proteins on plant growth and development.However,due to the large size of this protein family,the functions of most members remain largely unknown.Here,we summarize the molecular mechanisms of PPR proteins functions on organelle genes,and effects on development of organelles and plants.Problems that need to be resolved are also identified.This article will provide a theoretical basis for understanding the functions of PPR protein family and genetic improvements of grain yield and quality.

关 键 词：PPR蛋白 转录后调控 细胞器代谢 植株生长发育 

分 类 号：Q943[生物学—植物学]