卡马西平在UV/氯高级氧化工艺中的去除、转化与毒性评价  

Removal, transformation and toxicity evaluation of carbamazepine by the UV/chlorine advanced oxidation process

作　　者：袁霞 徐建业 吕贞[2] 茆永晶 杜尔登 郑璐 彭明国 丁朋飞 YUAN Xia;XU Jianye;LYU Zhen;MAO Yongjing;DU Erdeng;ZHENG Lu;PENG Mingguo;DING Pengfei(School of Environmental&Safety Engineering,Changzhou,213164,China;Office of Drainage Management,Changzhou,213016,China)

机构地区：[1]常州大学环境与安全工程学院,常州213164 [2]常州市排水管理处,常州213016

出　　处：《环境化学》2021年第10期3158-3170,共13页Environmental Chemistry

基　　金：国家水体污染控制与治理科技重大专项(2017X07202004);常州市科技支撑计划项目(CE20185027);江苏省国际科技合作项目(BZ2018019);江苏省高校优秀中青年教师和校长境外研修项目;江苏省研究生科研与实践创新计划项目(SJCX19_0690)资助。

摘　　要：UV/氯作为一种新型高级氧化工艺在新兴污染物控制领域引起了广泛关注.采用UV/氯工艺对典型抗癫痫药物卡马西平(CBZ)进行降解研究.比较单一UV、单一氯和UV/氯对CBZ的降解效果,考察了UV光强、余氯初始浓度、溶液初始pH值和氨氮浓度等因素的影响,解析CBZ在降解过程中的中间产物,提出降解机理,并评估生态风险.结果表明,UV/氯工艺的降解效果明显优于单一UV和单一氯.降解过程遵循准一级反应动力学.降解速率常数随UV光强和余氯初始浓度增大而增大,随氨氮浓度增加而减小,酸性条件更有利于降解过程.采用HRMS Orbitrap和GC-MS鉴定出10种CBZ降解中间产物,CBZ降解主要通过羟基化、氯取代和电子转移等反应实现.发光细菌毒性实验和ECOSAR预测均表明,CBZ在UV/氯工艺中会产生毒性高于母体的中间产物,对水质安全保障造成潜在风险.The UV/chlorine process has attracted wide attention as a new advanced oxidation process for emerging pollutant control. In this study, the degradation of the typical anti-epileptic drug carbamazepine(CBZ) was investigated by UV/chlorine process. The degradation of CBZ by single UV, single chlorine and UV/chlorine process was compared. Besides, the effects of UV light intensity, concentration of residual chlorine, pH of solution and ammonia nitrogen concentration on the degradation were also investigated. Built on the identification of degradation products, the degradation mechanism of carbamazepine(CBZ) in the UV/chlorine process was proposed. The ecological risk during the process was also evaluated. The results showed that the UV/chlorine process was more efficient than single UV and single chlorine. The whole process followed pseudofirst-order reaction kinetics. The degradation rate constants increased with the increase of UV light intensity and residual chlorine concentration, while decreased with the increasing ammonia nitrogen concentration. The acidic condition was in favor of the degradation process. Ten CBZ degradation intermediates were identified by HRMS Orbitrap and GC-MS. CBZ degradation was mainly achieved through hydroxylation, chlorine substitution and electron transfer. Both luminescent bacteria toxicity test and ECOSAR prediction indicated that the intermediates with higher toxicity than the parent could be generated during the UV/chlorine process, which may process the potential ecological risk for the water quality security.

关 键 词：卡马西平 UV/氯 高级氧化工艺 影响因素 降解机理 毒性评价 

分 类 号：X703[环境科学与工程—环境工程]