黄金微针射频联合超脉冲二氧化碳点阵激光治疗面部凹陷性痤疮瘢痕的疗效观察  

Evaluation of the efficacy of microneedle radiofrequency combined with ultra-pulse fractional carbon dioxide fractional laser in the treatment of facial atrophic acne scars

作　　者：李小燕 聂磊[1] 郭伟[1] 李琛[1] 孙波[1] 刘科峰[1] 程绍航[2] Li Xiaoyan;Nie Lei;Guo Wei;Li Chen;Sun Bo;Liu Kefeng;Cheng Shaohang(Department of Dermatology,First Affiliated Hospital of Henan University,Kaifeng 475000,China;不详)

机构地区：[1]河南大学第一附属医院皮肤科,开封475000 [2]中国医科大学盛京医院皮肤科

出　　处：《实用医技杂志》2021年第11期1279-1281,共3页Journal of Practical Medical Techniques

基　　金：河南省开封市科技发展计划项目(1903103)。

摘　　要：目的观察黄金微针射频联合超脉冲CO_(2)点阵激光治疗面部凹陷性瘢痕痤疮的疗效。方法我院门诊于2019年4月至2020年4月接收且诊治的74例凹陷性瘢痕痤疮患者为对象,随机分为2组,每组分别为37例。治疗组:首先采用超脉冲CO_(2)点阵激光治疗,间隔2周后再采取黄金微针射频治疗,二者交替治疗,连续交替治疗共8次为1个疗程。对照组:采用黄金微针射频治疗,治疗间隔时间4周,连续治疗4次;1个疗程结束后6个月随访,由我科2位未参与治疗的高级职称医生进行瘢痕权重评分(ECCA评分)和临床疗效分析、记录治疗引起的皮肤损伤相关时间指标。结果患者接受1个疗程治疗后6个月随访分析临床疗效。治疗前ECCA权重评分,治疗组评分为(52±20)分,对照组评分为(51±27)分,2组差异无统计学意义(Z=-0.637,P=0.524)。治疗前后ECCA权重评分,治疗组与对照组比较差异均有统计学意义(Z=-4.675,P<0.05;Z=-5.171,P<0.05)治疗组和对照组总体有效率分别为92%和73%,2组差异有统计学意义(χ^(2)=4.573,P<0.05)。治疗组患者的愈合时间、红肿持续时间和休工时间均低于对照组患者,差异均具有统计学意义(P<0.05)。结论黄金微针射频联合超脉冲CO_(2)点阵激光能够显著改善临床疗效,同时降低不良反应,且安全、有效,值得临床推广。Objective To observe the efficacy of microneedle radiofrequency combined with ultra-pulse fractional carbon dioxide(CO_(2))fractional laser in the treatment of facial atrophic acne scars.Methods A total of 74 patients with atrophic acne scars who were treated in our outpatient clinic from April 2019 to April 2020 were enrolled,and were randomly divided into 2 groups,with 37 subjects in each group.Treatment group:The patients were first treated with ultra-pulse fractional CO_(2) fractional laser,and then microneedle radiofrequency after 2 weeks.The two treatments were alternated for 8 consecutive treatments as a course of treatment.Control group:The patients were treated with microneedle radiofrequency,and the interval was 4 weeks,with 4 consecutive treatments as a course of treatment.After 6 months of follow-up after a course of treatment,two senior doctors in our department who were not involved in the treatment performed Echelle d′Evaluation Clinique des Cicatrices d′acne(ECCA)weighting scores and clinical efficacy analysis,and recorded postoperative adverse reactions.Results The patients were followed up for 6 months after receiving1 course of treatment,aiming to analyze the clinical efficacy.Before treatment,the ECCA weight score was(52±20)in the treatment group and(51±27)in the control group,without statistically significant differences between the two groups(Z=-0.637,P=0.524).After treatment,the ECCA weight score in the treatment group and the control group were reduced,with statistically significant differences(Z=-4.675,P<0.05;Z=-5.171,P<0.05).The overall effective rates of the treatment group and control group were 90%and 73%,respectively,and the differences between the two groups were statistically significant(χ^(2)=4.573,P<0.05).The healing time,redness,swelling duration and downtime of the treatment group were lower than those of the control group,and the difference was statistically remarkable(P<0.05).Conclusion Microneedle radiofrequency combined with ultra-pulse CO_(2) fractional laser can ob

关 键 词：寻常痤疮 瘢痕 激光疗法 激光 气体 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]