消癌平口服液联合支气管动脉介入灌注化疗术治疗中晚期肺癌的临床研究  

Clinical study on treating advanced lung cancer with the Xiaoaiping oral liquid plus bronchial artery interventional infusion chemotherapy

作　　者：孟令武[1] 周健[1] Meng Lingwu

机构地区：[1]商丘市第一人民医院,河南商丘476000

出　　处：《中医临床研究》2021年第23期36-38,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:探讨并分析消癌平口服液联合支气管动脉介入灌注化疗术治疗中晚期肺癌患者的临床效果。方法:选取84例中晚期肺癌患者随机分为对照组和试验组,各42例,对照组患者给予支气管动脉灌注化疗治疗,试验组患者在对照组的基础上联合使用消癌平口服液治疗,观察并比较两组治疗效果、骨髓抑制情况、中医证候评分,治疗前后生活质量评分、血清指标的变化情况。结果:试验组有效率较对照组更高(P <0.05);试验组白细胞减少率、血小板减少率均低于对照组(P <0.05),但是试验组血红蛋白减少率与对照组对比差异无统计学意义(P> 0.05);与对照组相比较,治疗后,试验组中医证候评分更低,卡氏功能状态评分更高(P <0.05);试验组中C反应蛋白、癌胚抗原、糖类抗原125均更低(P <0.05)。结论:临床上对中晚期肺癌患者进行治疗时,采用消癌平口服液联合支气管动脉介入灌注化疗治疗,能够有效改善临床症状及骨髓抑制,提高患者的生活质量,且治疗效果明显,有较高的推广价值。Objective:To explore and analyze the clinical efficacy of the Xiaoaiping oral liquid(消癌平口服液) plus bronchial artery interventional infusion chemotherapy on advanced lung cancer.Methods:84 cases were randomly divided into the control group and the experimental group,with 42 cases in each group.Patients in the control group were given bronchial arterial infusion chemotherapy,and the patients in the experimental group were treated with the Xiaoaiping oral liquid on the basis of the control group.Results:Efficiency in the experimental group was higher than the control group(P<0.05).The leukopenia rate and thrombocytopenia rate in the experimental group were lower than the control group(P<0.05).However,the reduction rate of hemoglobin in the experimental group was not statistically different from that in the control group(P>0.05).Compared with the control group,after treatment,the TCM syndrome score in the experimental group was lower,and the Karnofsky functional status score was higher(P<0.05).C-reactive protein,carcinoembryonic antigen and carbohydrate antigen 125 were all lower in the experimental group(P<0.05).Conclusion:The Xiaoaiping oral liquid plus bronchial artery interventional infusion chemotherapy on advanced lung cancer can effectively improve the clinical symptoms and bone marrow suppression,and the quality of life of the patients was improved.

关 键 词：消癌平口服液 支气管动脉介入灌注化疗术 中晚期肺癌 骨髓抑制 

分 类 号：R322.35[医药卫生—人体解剖和组织胚胎学]