对比^(18)F-FDG PET/CT与PET/MRI诊断胰腺占位性病变  

Comparison on ^(18)F-FDG PET/CT and PET/MRI for diagnosing space-occupying pancreatic lesions

作　　者：吴彪 弓健[1] 程勇[1] 唐勇进[1] 凌雪英[1] 徐浩[1] WU Biao;GONG Jian;CHENG Yong;TANG Yongjin;LING Xueying;XU Hao(Department of Nuclear Medicine,the First Affiliated Hospital of Jinan University,Guangzhou 510630,China)

机构地区：[1]暨南大学附属第一医院核医学科,广东广州510630

出　　处：《中国医学影像技术》2021年第11期1614-1618,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的比较^(18) F-FDG PET/CT与PET/MRI诊断胰腺占位性病变的价值。方法回顾性分析34例接受体部^(18) F-FDG PET/CT检查及上腹部MR扫描的胰腺占位患者,对比观察^(18) F-FDG PET/CT与PET/MRI判断良恶性病灶、图像融合匹配度、图像质量及图像附加信息,评估二者诊断胰腺占位性病变的价值。结果34例共检出37个胰腺病灶。PET/CT诊断7个良性病灶、30个恶性病灶,其诊断胰腺癌的敏感度、特异度和准确率分别为95.83%、46.15%和78.38%;PET/MRI诊断11个良性病灶、26个恶性病灶,其诊断胰腺癌的敏感度、特异度和准确率分别为100%、84.61%和94.59%,诊断准确率显著高于PET/CT(χ^(2)=4.16,P=0.04)。PET/CT与PET/MR图像融合匹配度差异无统计学意义(P>0.05)。CT、MR、PET/CT及PET/MR图像质量差异无统计学意义(P>0.05)。27.03%(10/37)的图像附加信息评分为-1分,8.11%(3/37)为0分,64.86%(24/37)为1分。结论PET/MRI诊断胰腺癌的敏感度、特异度、图像融合匹配度及图像质量均与PET/CT相近,而其诊断准确率高于PET/CT,有助于诊断及鉴别胰腺占位性病变。Objective To compare the value of ^(18)F-FDG PET/CT and PET/MRI for diagnosing space-occupying pancreatic lesions.Methods Data of 34 patients with space-occupying pancreatic lesions who underwent whole-body ^(18)F-FDG PET/CT and upper abdominal MR examination were retrospectively analyzed.The nature of lesions,image fusion matching degree,image quality and additional information of ^(18)F-FDG PET/CT and PET/MRI were observed and compared,and the values of diagnosing space-occupying pancreatic lesions were assessed.Results Totally 37 lesions were detected in 34 patients.PET/CT diagnosed 7 benign lesions and 30 malignant ones,the sensitivity,specificity and accuracy of PE/CT for diagnosing pancreatic cancer was 95.83%,46.15%and 78.38%,respectively.PET/MRI diagnosed 11 benign lesions and 26 malignant ones,the sensitivity,specificity and accuracy was 100%,84.61%and 94.59%,respectively.The diagnostic accuracy of PET/MRI was significantly higher than that of PET/CT(χ^(2)=4.16,P=0.04).There was no significant difference of image fusion matching degrees between PET/CT and PET/MRI(P>0.05),nor of image quality among CT,MRI,PET/CT and PET/MRI(P>0.05).The additional image information score of 27.03%(10/37)lesions was-1,of 8.11%(3/37)was 0,while of 64.86%(24/37)was 1.Conclusion The sensitivity and specificity for diagnosing pancreatic cancer,image fusion matching degree and image quality of PET/MRI were similar to those of PET/CT,while the diagnostic accuracy of PET/MRI was higher than that of PET/CT,hence being helpful for diagnosing and differential space-occupying pancreatic lesions.

关 键 词：胰腺肿瘤 胰腺炎 磁共振成像 正电子发射断层显像 18F氟脱氧葡萄糖 

分 类 号：R657.5[医药卫生—外科学] R445[医药卫生—临床医学]