季铵盐聚砜/聚乙烯醇/单宁酸复合水凝胶的制备及性能  

Preparation and Properties of Quaternary Ammonium Polysulfone/Polyvinyl Alcohl/Tannin Composite Hydrogels

作　　者：杨明成[1] 陈阳[1] 张本尚[1] 张秋霞 刘树博[1] 郭文慧 YANG Mingcheng;CHEN Yang;ZHANG Benshang;ZHANG Qiuxia;LIU Shubo;GUO Wenhui(Isotope Institute Co.Ltd.,Henan Academy of Sciences,Henan Provincial Research Center of Engineering&Technology for Radation Tectnology and New Materials,Zhengzhou 450015,China;Henan Provincial Research Center of Engineering&Technology for Eye Care Products,Zhengzhou 450003,China)

机构地区：[1]河南省科学院同位素研究所有限责任公司,河南省辐射新材料工程技术研究中心,郑州450015 [2]河南省眼健康产品工程技术研究中心,郑州450003

出　　处：《吉林大学学报（理学版）》2021年第6期1593-1601,共9页Journal of Jilin University:Science Edition

基　　金：中原科技创新领军人才项目(批准号:194200510030);河南省科学院科技开放合作项目(批准号:200904007);河南省科学院基本科研基金(批准号:190604016,200604025).

摘　　要：以聚砜为原料,通过氯甲基化反应制备高取代度的氯甲基化聚砜,与三甲胺溶液反应后经透析、冷冻干燥得到具有抑菌性且溶于水的季铵盐聚砜.季铵盐聚砜与聚乙烯醇水溶液互溶后,采用γ射线辐射交联的方法,无需添加交联剂即可得到季铵盐聚砜/聚乙烯醇水凝胶,解决了聚砜类水凝胶中有机溶剂和其他辅助试剂残留的问题,同时还使水凝胶具有抑菌性能,可用于制备医用伤口敷料.Chloromethylated polysulfone with high degree of substitution was prepared from polysulfone as raw materials by chloromethylation reaction,after reacting with trimethylamine solution,the quaternary ammonium polysulfone with bacteriostatic properties and water-soluble was obtained by dialysis and freeze-drying.The quaternary ammonium polysulfone reacted with polyvinyl alcohol aqueous solution,the quaternary ammonium polysulfone/polyvinyl alcohol hydrogels could be obtained by cross-linkingγ-ray radiation without addition of cross-linking agent.The problem of residual organic solvents and other auxiliary reagents in the polysulfone hydrogels was solved,at the same time,the hydrogels had bacteriostatic properties and could be used for preparing medical wound dressings.

关 键 词：聚乙烯醇 季铵盐聚砜 单宁酸 复合水凝胶 

分 类 号：O632[理学—高分子化学]