腹腔镜结直肠癌手术与开放性手术的疗效及安全性分析  

Analysis of the Efficacy and Safety of Laparoscopic Colorectal Cancer Surgery and Open Surgery

作　　者：尹小波 YIN Xiaobo(Department of General Surgery,the Third People's Hospital of Rugao City,Rugao,Jiangsu Province,226531 China)

机构地区：[1]如皋市第三人民医院普外科,江苏如皋226531

出　　处：《中外医疗》2021年第26期41-44,共4页China & Foreign Medical Treatment

摘　　要：目的分析结直肠癌患者实施开放性手术与腹腔镜手术效果差异。方法于2017年1月—2020年1月方便选取在该院进行结直肠癌手术干预患者88例作为研究群体。依据随机投掷硬币单双面法将其分成44例的常规组和44例的研究组,其中常规组患者开放性手术治疗,予以研究组患者腹腔镜手术治疗。对比两组患者手术过程中出血量、手术时间、肠功能恢复时间以及住院总时间;并发症出现率;手术前后白细胞介素-6以及白细胞介素-8水平;生活质量恢复情况。结果在手术过程中出血量方面,研究组低于常规组;在手术时间方面,研究组高于常规组;在肠功能恢复时间以及住院总时间方面,研究组低于常规组,差异有统计学意义(P<0.05)。研究组与常规组患者并发症总出现率依次是4.55%、20.45%,差异有统计学意义(χ^(2)=5.091,P<0.05)。研究组患者手术后第1天、第3天白细胞介素-6依次是(115.32±27.31)、(78.25±20.09)pg/mL,白细胞介素-8水平依次是(35.39±10.17)、(18.12±5.03)μg/L,均低于常规组(285.66±60.21)、(174.29±30.04)pg/mL、(58.09±15.32)、(29.58±9.01)μg/L,差异有统计学意义(t=17.090、17.628、8.189、7.367,P<0.05)。研究组与常规组患者生活质量恢复总有效率依次是95.45%、81.82%,差异有统计学意义(χ^(2)=4.062,P<0.05)。结论结直肠癌患者采用腹腔镜手术治疗可减少出血量,对患者机体损伤较小,同时手术后并发症较少,可促进患者机体恢复,缩短住院时间,提升其生活质量水平,发挥一定临床应用效果。Objective To compare the effects of open surgery and laparoscopy on treatment of colorectal cancer.Methods 88 colorectal cancer patients treated from January 2017 to January 2020 in the hospital were conveniently selected and assigned to routine group(44 cases)and test group(44 cases)according to random number table.The routine group received the open surgery;the test group received the laparoscopy.Group contrasts were performed about the intraoperative bleeding volume,operation time,intestinal function recovery time and overall hospital stays,complication rate,Interleukin-6 and Interleukin-8 levels as well as life quality.Results In terms of blood loss during surgery,the study group was lower than the routine group;in terms of operation time,the study group was higher than the routine group;in terms of bowel function recovery time and total hospital stay,the study group was lower than the routine group,the difference was statistically significant(P<0.05).The total incidence of complications in the study group and the routine group was 4.55%and 20.45%in sequence,and the difference was statistically significant(χ^(2)=5.091,P<0.05).The interleukin-6 levels of the patients in the study group were(115.32±27.31)pg/mL and(78.25±20.09)pg/mL on the first day and the third day after surgery,and the levels of interleukin-8 were(35.39±10.17)μg/L,(18.12±5.03)μg/L,were lower than the conventional group(285.66±60.21)pg/mL,(174.29±30.04)pg/mL,(58.09±15.32)μg/L,(29.58±9.01)μg/L,the difference was statistically significant(t=17.090,17.628,8.189,7.367,P<0.05).The total effective rate of quality of life restoration of patients in the study group and the routine group was 95.45%and 81.82%,respectively,and the difference was statistically significant(χ^(2)=4.062,P<0.05).Conclusion The laparoscopy can reduce the bleeding volume,clinical trauma and postoperative complications,promote the fast recovery,shorten the hospital stays and improve the life quality.

关 键 词：安全性 效果 开放性手术 腹腔镜 结直肠癌 

分 类 号：R6[医药卫生—外科学]