早期食管癌及食管癌前病变实施内镜黏膜下剥离术治疗的特点及效果分析  

The Characteristics and Effect Analysis of Endoscopic Submucosal Dissection for Early Esophageal Cancer and Precancerous Lesions of the Esophagus

作　　者：尹成龙 朱华[1] YIN Chenglong;ZHU Hua(Department of Gastroenterology,Yancheng Third People's Hospital,Yancheng,Jiangsu Province,224000 China)

机构地区：[1]盐城市第三人民医院消化内科,江苏盐城224000

出　　处：《中外医疗》2021年第26期61-64,共4页China & Foreign Medical Treatment

基　　金：2015年盐城市医学科技发展计划项目(YK2015103)。

摘　　要：目的分析对早期食管癌及食管癌前病变患者实施内镜黏膜下剥离术治疗的特点表现及临床疗效。方法笑意随机选取2019年1月—2020年1月在该院收治的80例早期食管癌及食管癌前病变患者,其均接受内镜黏膜下剥离术(ESD),并进行回顾性分析患者在完整和整块切除率、各项手术指标、并发症及复发情况等临床信息,总结实施内镜黏膜下剥离术治疗的特点及效果。结果患者完整切除率和整块切除率分别为95.00%、97.50%;手术用时及最大病灶直径分别为(52.63±7.22)min、(26.35±5.12)mm,在术中出血量及住院用时上分别为(68.15±6.22)mL、(8.83±1.52)d;所有患者术后出血和穿孔发生率、食管狭窄发生率分别为2.50%、3.75%、6.25%。仅在术后12个月出现2例复发患者,总复发率为2.50%。结论ESD对早期食管癌及癌前病变患者可一次性安全、有效地完整切除病灶,有手术用时短、复发率较低的优势,但其术后食管狭窄发生率较高。Objective To analyze of the characteristics and clinical effects of endoscopic submucosal dissection for patients with early esophageal cancer and precancerous lesions of the esophagus.Methods Simple random selected 80 patients with early esophageal cancer and precancerous lesions of the esophagus who were admitted to the hospital from January 2019 to January 2020.All of them underwent endoscopic submucosal dissection(ESD),and a retrospective analysis was performed.Clinical information such as mass resection rate,various surgical indicators,complications and recurrence,and summarize the characteristics and effects of endoscopic submucosal dissection.Results The patient's complete resection rate and en bloc resection rate were 95.00%and 97.50%,the operation time and maximum lesion diameter were(52.63±7.22)min and(26.35±5.12)mm,respectively.Intraoperative blood loss and hospitalization time were(68.15±6.22)mL and(8.83±1.52)d;the incidence of postoperative bleeding and perforation,and the incidence of esophageal stenosis were 2.50%,3.75%,and 6.25%in all patients.Only 2 patients with recurrence occurred 12 months after surgery,and the total recurrence rate was 2.50%.Conclusion ESD can safely and effectively complete the resection of the lesions in patients with early esophageal cancer and precancerous lesions.It has the advantages of short operation time and low recurrence rate,but the incidence of postoperative esophageal stenosis is relatively high.

关 键 词：早期食管癌 食管癌前病变 内镜黏膜下剥离术 

分 类 号：R4[医药卫生—临床医学]