全麻气管拔管期运用小剂量瑞芬太尼联合地佐辛的临床效果研究  

Study on the Clinical Effect of Low-dose Remifentanil Combined with Dezocine during Extubation of General Anesthesia

作　　者：夏静[1] 钱宁[1] XIA Jing;QIAN Ning(Department of Anesthesiology,Taizhou Second People's Hospital,Taizhou,Jiangsu Province,225500 China)

机构地区：[1]泰州市第二人民医院麻醉科,江苏泰州225500

出　　处：《中外医疗》2021年第26期88-91,共4页China & Foreign Medical Treatment

摘　　要：目的研究在全麻气管拔管期运用小剂量瑞芬太尼联合地佐辛的临床效果。方法方便选取2019年3月—2020年11月该院收治的88例行全麻手术治疗的患者作为研究对象,并根据随机数字表法分为两组,对照组患者(n=44例)在手术结束后停止使用瑞芬太尼,研究组患者(n=44例)则继续进行瑞芬太尼小剂量泵注。比较分析两组全麻手术患者的血流动力学指标、术后不良反应及苏醒时间和拔管时间等指标。结果研究组患者拔管后1 min、拔管后3 min和拔管后5 min的SaO_(2)分别为(98.96±2.08)%、(99.56±1.23)%、(99.87±1.34)%,明显优于对照组相关指标,差异有统计学意义(t=3.112、4.981、6.057,P<0.05);研究组患者拔管后1 min、拔管后3 min和拔管后5 min的HR分别为(77.45±7.83)次/min、(88.54±9.17)次/min、(86.73±8.62)次/min,明显优于对照组相关指标,差异有统计学意义(t=3.870、4.696、5.243,P<0.05);研究组患者拔管后1 min、拔管后3 min和拔管后5 min的MAP分别为(90.42±8.23)mmHg、(108.24±14.53)mmHg、(106.35±12.21)mmHg,明显优于对照组相关指标,差异有统计学意义(t=2.041、2.996、2.867,P<0.05);研究组术后不良反应的发生率为9.09%,明显低于对照组的29.55%,差异有统计学意义(χ^(2)=5.906,P<0.05);研究组的苏醒时间为(8.04±0.92)min,拔管时间为(9.31±1.02)min,均明显短于对照组,差异有统计学意义(t=5.171,4.093,P<0.05)。结论在全麻气管拔管期给予患者小剂量瑞芬太尼联合地佐辛具有确切的应用效果。Objective To study the clinical effects of low-dose remifentanil combined with dezocine during the extubation period of general anesthesia.Methods 88 patients undergoing general anesthesia surgery in the hospital from March 2019 to November 2020 were conveniently selected as the research object,and were divided into two groups according to the random number table method.The patients in the control group(n=44 cases)stopped using remifentanil after the operation,and the patients in the study group(n=44 cases)continued to use remifentanil low-dose pump injection.The hemodynamic indexes,postoperative adverse reactions,recovery time and extubation time of the two groups were compared and analyzed.Results SaO_(2) of patients in the study group were(98.96±2.08)%,(99.56±1.23)%,(99.87±1.34)%at 1 min,3 min and 5 min after extubation,respectively,which were significantly better than those in the control group,and the difference was statistically significant(t=3.112,4.981,6.057,P<0.05);the HR of patients in the study group were(77.45±7.83)times/min,(88.54±9.17)times/min,(86.73±8.62)times/min at 1 min,3 min and 5 min after extubation,respectively,significantly better than the control group,and the difference was statistically significant(t=3.870,4.696,5.243,P<0.05).MAP of patients in the study group were(90.42±8.23)mmHg,(108.24±14.53)mmHg,(106.35±12.21)mmHg at 1 min,3 min and 5 min after extubation,respectively,significantly better than the control group,and the difference was statistically significant(t=2.041,2.996,2.867,P<0.05).The incidence of postoperative adverse reactions in the study group was 9.09%,which was significantly lower than 29.55%in the control group,and the difference was statistically significant(χ^(2)=5.906,P<0.05).The awakening time and extubation time of the study group were(8.04±0.92)min and(9.31±1.02)min,respectively,which were significantly shorter than those of the control group,and the difference was statistically significant(t=5.171,4.093,P<0.05).Conclusion It is effective to give patie

关 键 词：全麻 气管拔管 瑞芬太尼 地佐辛 

分 类 号：R614[医药卫生—麻醉学]