PIVAS成品输液微粒相关风险因素及处理措施研究  

Research on Risk Factors and Treatment Measures Related to PIVAS Finished Infusion Particles

作　　者：陈刚 叶思成 李菊芳 花萍 CHEN Gang;YE Sicheng;LI Jufang;HUA Ping(Department of Pharmacy,Dongtai Hospital,Nantong University,Dongtai,Jiangsu Province,224200 China;Department of Pharmacy,Suzhou Ninth People's Hospital,Suzhou,Jiangsu Province,215200 China)

机构地区：[1]南通大学附属东台医院药学科,江苏东台224200 [2]苏州市第九人民医院药剂科,江苏苏州215200

出　　处：《中国卫生产业》2021年第21期1-3,8,共4页China Health Industry

基　　金：盐城市医学科技发展计划项目(YK2018106)。

摘　　要：目的探讨影响南通大学附属东台医院静脉用药调配中心(PIVAS)成品输液微粒相关风险因素与处理措施。方法回顾性分析2019年7—12月应用该院PIVAS配置的126583袋药物,对加药调配或核对时发现的与输液微粒有关质量问题进行记录,总结影响PIVAS成品输液微粒相关风险因素,并实施针对性处理,以2020年5—10月为处理后阶段,比较处理前后的输液微粒风险事件的发生情况。结果多因素Logistic回归分析显示,配置操作不规范、注射器选择不合理与需反复抽吸为引发PIVAS成品输液微粒相关风险事件的独立危险因素(P<0.05);针对性处理后PIVAS成品输液微粒相关风险事件发生率低于处理前,差异有统计学意义(P<0.05)。结论PIVAS成品输液微粒相关风险因素主要为配置操作不规范、注射器选择不合理与需反复抽吸,通过规范配置操作,合理选择注射器可降低风险因数发生。Objective To investigate the risk factors and treatment measures that affect the particulates related to the infusion of finished products in the intravenous drug distribution center(PIVAS)of Dongtai hospital affiliated to nantong university.Methods A retrospective analysis of 126583 bags of drugs prepared by PIVAS in the hospital from July to December 2019 was used to record the quality problems related to infusion particles found during dosing and compounding or check,and summarize the impact on PIVAS products Infusion particulate-related risk factors,and targeted treatment will be implemented.With May to October 2020 as the post-treatment stage,compare the occurrence of infusion particulate risk events before and after treatment.Results Multi-factor Logistic regression analysis showed that irregular configuration and operation,unreasonable syringe selection,and repeated aspiration were independent risk factors for risk events related to PIVAS product infusion particles(P<0.05);after targeted treatment,the incidence of PIVAS product infusion particles related risk events was lower than before treatment,and the difference was statistically significant(P<0.05).Conclusion The risk factors related to the infusion particles of PIVAS products are mainly irregular configuration operations,unreasonable syringe selection and repeated aspiration.Through standardized configuration operations and reasonable selection of syringes,risk factors can be reduced.

关 键 词：静脉用药调配中心 输液微粒 风险因素 多因素分析 处理措施 

分 类 号：R19[医药卫生—卫生事业管理]