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作 者:梁志恒 李运伦[2] 张磊[2] 魏秀娟 LIANG Zhiheng;LI Yunlun;ZHANG Lei;WEI Xiujuan(Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Liaocheng Dongchangfu District Hospital of Traditional Chinese Medicine,Liaocheng 252000,China)
机构地区:[1]山东中医药大学,山东济南250355 [2]山东中医药大学附属医院,山东济南250014 [3]聊城市东昌府区中医院,山东聊城252000
出 处:《山东中医药大学学报》2021年第6期776-781,共6页Journal of Shandong University of Traditional Chinese Medicine
基 金:国家自然科学基金面上项目(编号:81974561);山东省自然科学基金博士基金项目(编号:ZR2017BH091、ZR2019BH033);中国博士后科学基金项目(编号:2017M612342);山东省保健科技协会科学技术课题(编号:SDBJKT20170080);山东省中医药科技发展计划项目(编号:2017-048、2017-055);齐鲁卫生与健康杰出青年人才项目资助、中西医结合心血管泰山学者工程专项经费资助。
摘 要:目的:运用层次分析法和德尔菲法对扩张型心肌病(DCM)的中医病因及危险因素进行问卷调查,初步建立量化的DCM中医病因系统层次分析模型,确定各因素的相对权重总排序。方法:在前期文献研究及模型初步构建的基础上,根据专家运用Satty法对判断矩阵做出的评分,通过一系列的定量运算得出各病因最大特征根λmax及各因素对应的特征向量W,通过归一化处理最终得出权重总排序。结果:各因素的相对权重排序准则层为自然因素>家族史>其他因素>生活因素>继发因素,因素层为邪毒>先天禀赋>六淫>体弱>劳逸失度>饮食>七情>(瘀毒=他病传变)>胎产>瘀血>痰浊>药邪>(水饮=性别)>肥胖。结论:外感邪毒或六淫、禀赋不足、体弱、劳逸失度、瘀毒等因素与DCM的发病有较强相关性,此对临床有针对性进行DCM的“辨证求因”及“审因论治”有一定的参考意义,但部分专家意见尚与综合结果存有较大差异,有待于新一轮的问卷调查以获得更准确的结果。Objective:Use the analytic hierarchy process(AHP)and Delphi method to conduct a questionnaire survey on the causes and risk factors of dilated cardiomyopathy(DCM)in Chinese medicine,and establish an AHP model of TCM etiology of DCM,determine the relative weight of each factor. Methods:On the basis of the preliminary literature research and model construction,according to the expert’s evaluation of the judgement matrix using the Satty method,the largest characteristic root λmax of each etiology and the corresponding characteristic vector W of each factor are obtained through a series of quantitative calculations. Through the normalization process,the total ranking of the weights is finally obtained. Results:The relative weight of each factor is sorted as the criterion level:natural factors>family history>other factors>life factors>secondary factors. The factor level:pathogenic toxin>innate endowment>six exogenous pathogens>weakness>overstrain>diet>seven emotions>(stasis toxin=other disease transmission)>fetal birth>blood stasis>phlegm turbidity>medicinal pathogen>(retained fluid=gender)>obesity. Conclusions:Exogenous pathogenic toxin or six exogenous pathogens,insufficient endowment,weakness,over strain,and static toxin have a strong correlation with the onset of DCM. The clinically targeted “syndrome differentiation to determine disease cause” and “examining causes and treatment” have certain reference significance,but some expert opinions are still quite different from the comprehensive results,and a new round of questionnaire survey is needed to obtain more accurate results.
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