高血压病与子宫肌瘤相关性中西医研究进展  

Research Progress of Traditional Chinese Medicine and Western Medicine on Correlation Between Essential Hypertension and Uterine Fibroids

作　　者：张凌霄 李运伦[1] 张磊[1] 张延宇 于杰[2] ZHANG Lingxiao;LI Yunlun;ZHANG Lei;ZHANG Yanyu;YU Jie(Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]山东中医药大学,山东济南250355 [2]山东中医药大学附属医院,山东济南250014

出　　处：《山东中医药大学学报》2021年第6期842-848,共7页Journal of Shandong University of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(编号:81774242)。

摘　　要：近年来流行病学研究表明,高血压病与子宫肌瘤之间互相影响,在高血压人群中,子宫肌瘤的发病风险与血压升高呈正相关;有子宫肌瘤病史的妇女患高血压病的概率更高,提示高血压病和子宫肌瘤可能存在共同的发病机制。结合近年来相关临床研究,提出二者可能的共同发病机制包括尿路梗阻学说、动脉粥样硬化学说、共同调节因子学说、肾素-血管紧张素-醛固酮系统(RAAS)学说。并从中医学角度提出肝、肾为二病的共同病位,肾虚血瘀、肝郁气滞为其发病的共同病因病机,治法当以补肾活血、疏肝理气为要。参考文献55篇。In recent years,epidemiological studies have shown that essential hypertension and uterine fibroids affect each other.In hypertensive people,the risk of uterine fibroids is positively correlated with increased blood pressure.Women with a history of uterine fibroids are more likely to develop essential hypertension,suggesting that essential hypertension and uterine fibroids may have the common pathogenesis.Combining with relevant clinical studies in recent years,it is proposed that the possible common pathogenesis of the two diseases include urinary obstruction theory,atherosclerosis theory,co-regulatory factor theory,renin-angiotensin-aldosterone system(RAAS)theory.From the perspective of traditional Chinese medicine,it is proposed that liver and kidney are the common disease locations,and kidney deficiency and blood stasis,liver depression and qi stagnation are the common etiology and pathogenesis of the diseases.The treatment should be based on tonifying kidney and activating blood,soothing liver and regulating qi. There are 55 references in total.

关 键 词：高血压病 子宫肌瘤 动脉粥样硬化学说 尿路梗阻学说 共同调节因子学说 肾虚血瘀 肝郁气滞 

分 类 号：R259.441[医药卫生—中西医结合] R271.1[医药卫生—中医内科学]