右美托咪定滴鼻预防再次剖宫产术中牵拉痛的临床效果分析  

Clinical Effect Analysis of Dexmedetomidine Nasal Drops in Preventing Traction Pain during Re-cesarean Section

作　　者：邢文彦 XING Wenyan(Department of Anesthesiology,Maternal and Child Health Hospital of Inner Mongolia Autonomous Region,Hohhot,Inner Mongolia Autonomous Region,010020 China)

机构地区：[1]内蒙古自治区妇幼保健院麻醉科,内蒙古呼和浩特010020

出　　处：《系统医学》2021年第18期56-58,共3页Systems Medicine

摘　　要：目的观察右美托咪定滴鼻预防再次剖宫产术中牵拉痛的临床效果。方法选取内蒙古自治区妇幼保健院2019年5—7月接收的200例再次剖宫产术患者为该次研究对象,按照是否在连续硬膜外麻醉前10 min右美托咪定滴鼻将患者分为对照组(100例,未应用右美托咪定滴鼻而给予1 mL生理盐水滴鼻)与治疗组(100例,1 mL右美托咪定滴鼻),比较两组患者预后。结果治疗组患者硬膜外麻醉给药10 min后(T1)平均动脉压(MAP)、心率(HR)等血流动力学指标分别为(90.75±2.44)mmHg、(74.54±2.44)次/min,新生儿娩出时(T2)上述血流动力学指标分别为(88.54±2.45)mmHg、(72.32±2.43)次/min,同期血流动力学指标均优于对照组,差异有统计学意义(t=10.932、31.682、13.824、34.977,P<0.05)。治疗组患者T1、T2视觉模拟评分法(VAS)评分分别为(2.23±0.11)分、(2.32±0.11)分,均低于对照组,差异有统计学意义(t=88.161、117.330,P<0.05)。治疗组新生儿二氧化碳分压(PCO2)、氧分压(PO2)及脐动脉血pH值(pH)等脐动脉血血气分析结果分别为(52.32±2.33)mmHg、(14.54±2.32)mmHg、(7.54±0.11),与对照组对比,差异无统计学意义(t=0.091、0.121、1.843,P>0.05)。结论再次剖宫产术患者右美托咪定滴鼻可有效预防术中牵拉痛。Objective To observe the clinical effect of dexmedetomidine nasal drops in preventing traction pain during re-cesarean section.Methods Selected Inner Mongolia Autonomous Region Maternal and Child Health Hospital received 200 patients undergoing re-cesarean section from May to July 2019 as the subjects of this study.The patients were divided according to whether they were infused with dexmedetomidine 10 minutes before continuous epidural anesthesia.Compared the prognosis of the two groups were the control group(100 cases,1 mL of saline infusion without dexmedet omidine nasal drip)and the therapy group(100 cases,1 mL of dexmedetomidine in the nasal drip).Compared the prognosis of the two groups of patients.Results The hemodynamic indexes such as mean arterial pressure(MAP)and heart rate(HR)of the therapy group were(90.75±2.44)mmHg and(74.54±2.44)times/min after the administration of epidural anesthesia for 10 minutes.At the time of delivery(T2),the above hemodynamic indexes were(88.54±2.45)mmHg and(72.32±2.43)times/min,respectively.The hemodynamic indexes during the same period were better than those of the control group,the difference was statistically significant(t=10.932,31.682,13.824,34.977,P<0.05).The T1 and T2 visual pain VAS scale scores of the therapy group were(2.23±0.11)points and(2.32±0.11)points,respectively,which were lower than those of the control group,the difference was statistically significant(t=88.161,117.330,P<0.05).The results of umbilical arterial blood gas analysis such as partial pressure of carbon dioxide(PCO2),partial pressure of oxygen(PO2)and umbilical artery blood pH(pH)in the therapy group were(52.32±2.33)mmHg,(14.54±2.32)mmHg,(7.54±0.11),there was no significant difference from the control group,and the data was not significantly different(t=0.091,0.121,1.843,P>0.05).Conclusion Dexmedetomidine nasal drops in patients undergoing re-cesarean section can effectively prevent intraoperative traction pain.

关 键 词：右美托咪定滴鼻 预防 再次剖宫产术 牵拉痛 

分 类 号：R614[医药卫生—麻醉学]