非均匀材料股骨在不同负荷情况下的生物力学分析  

Biomechanical analysis of non-uniform material femur under different loads

作　　者：魏国强 李云峰 王一 牛晓芬 车丽芳 王海燕 李志军 史国鹏 白灵 莫凯 张晨晨 许阳阳 李筱贺 Wei Guoqiang;Li Yunfeng;Wang Yi;Niu Xiaofen;Che Lifang;Wang Haiyan;Li Zhijun;Shi Guopeng;Bai Ling;Mo Kai;Zhang Chenchen;Xu Yangyang;Li Xiaohe(Department of Rehabilitation Medicine,Changzhi City People’s Hospital,Changzhi 046000,Shanxi Province,China;Department of Anatomy,School of Basic Medicine,Inner Mongolia Medical University,Hohhot 010110,Inner Mongolia Autonomous Region,China;Center for Digital Medicine,Inner Mongolia Medical University,Hohhot 010110,Inner Mongolia Autonomous Region,China)

机构地区：[1]长治市人民医院康复医学科,山西省长治市046000 [2]内蒙古医科大学基础医学院解剖教研室,内蒙古自治区呼和浩特市010110 [3]内蒙古医科大学数字医学中心,内蒙古自治区呼和浩特市010110

出　　处：《中国组织工程研究》2022年第9期1318-1322,共5页Chinese Journal of Tissue Engineering Research

基　　金：国家自然科学基金(81460330),项目负责人:李筱贺;国家自然科学基金(81560348,81860383,81260269),项目负责人:李志军;内蒙古自治区科技计划项目(2019),项目负责人:李筱贺;内蒙古教育厅青年科技英才项目(njyt-15-b05),项目负责人:李筱贺;内蒙自治区科技计划项目(2016),项目负责人:李筱贺;内蒙自治区科技计划项目(2019GG115),项目负责人:李志军;内蒙古自治区科技创新引导项目(2017),项目负责人:李筱贺;内蒙古自治区自然科学基金(2016MS08131,2020MS08124,2020LH08021),项目负责人:李筱贺;内蒙古人社厅归国留学人员基金,项目负责人:李筱贺;内蒙古医科大学科技百万计划基金项目(YKD2017KJBW012),项目负责人:王海燕;内蒙古医科大学后续科研项目(2020),项目负责人:李筱贺;内蒙古医科大学科技转化项目(YKD2020CGZH009),项目负责人:李筱贺;内蒙古自治区“草原英才”工程青年创新人才,项目负责人:李筱贺;内蒙古医科大学“治学”人才二类(2021),项目负责人:李筱贺。

摘　　要：背景:目前股骨有限元模型仅分析单一负荷下的生物力学特性,不同负荷条件下的骨应力应变分布有助于评估和预测疾病恢复情况并改善手术效果。目的:通过建立股骨三维模型,探索人体在不同姿势下股骨近端力学分布特点,明确股骨易骨折危险区域。方法:基于人体股骨CT影像资料,利用Mimics,Geomagic Studio,Hypermesh以及Abaqus等三维重建软件建立股骨有限元模型,沿重力方向,在股骨冠状面与矢状面,分别成角-20°,-10°,0°,+10°,+20°,共5组工况,股骨头施加力300 N,股骨下段添加固定约束,观察股骨不同位置在不同角度生理负荷作用下的应力与应变的分布特征。结果与结论:在冠状面+10°与矢状面-20°股骨的应力值与应变值出现峰值,股骨应力值整体分布:股骨干>股骨转子下>股骨颈,股骨应变值整体分布:股骨干>股骨颈>股骨转子下。患者髋内收10°站立位下与髋外展20°站立位下会使得股骨应力值与应变值增大,股骨整体力学所受负荷会增大。BACKGROUND:The current femoral finite element model analyzes only the biomechanical studies at a single load,and the stress strain distribution of the bones under different load conditions helps to evaluate and predict the disease recovery and improve the surgical results.OBJECTIVE:Through the establishment of a three-dimensional model of the femur,to explore the mechanical behavior of the proximal femur in different postures of the human body,and clarify the risk area of femur fracture.METHODS:Based on the CT image data of the human femur,Mimics,Geomagic Studio,Hypermesh and Abaqus and other three-dimensional reconstruction softwares were used to establish a finite element model of the femur.Along the direction of gravity,on the coronal and sagittal planes of the femur,the shape surfaces were angled at-20°,-10°,0°,+10°,+20°,a total of five groups of working conditions,and the femoral head exerted a force of 300 N.The lower part of the femur added a fixed constraint.At different positions of the femur,the distribution characteristics of stress and strain were observed under angular physiological load.RESULTS AND CONCLUSION:The stress and strain of the femur peaked at+10°in the coronal plane and-20°in the sagittal plane.The overall distribution of femoral stress values was femoral shaft>subtrochanteric>femoral neck;the overall distribution of femoral strain values was femoral shaft>femoral neck>subtrochanteric.The stress value and strain value of the femur could increase under the standing position of 10°hip adduction and 20°of hip abduction,and the load on the overall mechanics of the femur could increase.

关 键 词：股骨 三维重建 有限元分析 应力 应变 

分 类 号：R459.9[医药卫生—治疗学] R318[医药卫生—临床医学]