青少年脊柱侧弯全脊柱生物力学模型的构建及验证  

Construction and verification of a full spine biomechanical model of adolescent scoliosis

作　　者：张玉芳 吕蒙[1] 梅钊 Zhang Yufang;Lü Meng;Mei Zhao(Zhengzhou Railway Vocational and Technical College,Zhengzhou 450000,Henan Province,China;Huazhu Medical Technology(Shanghai)Co.,Ltd.,Shanghai 200120,China)

机构地区：[1]郑州铁路职业技术学院,河南省郑州市450000 [2]华柱医疗科技(上海)有限公司,上海市200120

出　　处：《中国组织工程研究》2022年第9期1351-1356,共6页Chinese Journal of Tissue Engineering Research

摘　　要：背景:现阶段脊柱侧弯患者的生物力学模型过于简化,未建立完整的患者躯干骨骼-肌肉有限元模型,并缺少软组织力学特性的建模。目的:构建一个真实且具有详细解剖学结构的脊柱侧弯躯干有限元模型,并对其有效性进行验证。方法:选择1例11岁青少年脊柱侧弯患者,通过64排螺旋CT扫描获得.Dicom格式的原始数据,建立其躯干有限元模型,并进行有效性验证,将腰骶段模型和躯干模型的模拟结果分别与已公开发表的文献中实验结果进行对比验证。研究方案的实施符合鹤壁市人民医院的相关伦理要求(医院伦理批件号YK2019015)。结果与结论:①模型的建立:整个躯干有限元模型包括8470000余个单元,1690000余个节点;②腰骶段模型验证:建立的模型在屈伸、侧屈和扭转情况下的平均刚度分别为7.15,2.56,1.92 N·m/(°),该值介于文献报道的实验结果之间,加载结果与文献中的实验值一致;③躯干模型的验证:在3种束带张力(20,40和60 N)作用下,脊柱的应力值变化均介于文献报道的实验结果的中间;④构建的1例具有详细解剖学结构的青少年脊柱侧弯躯干生物力学模型,通过生物力学模型有效性验证,该模型可靠、合理且真实、直观地显示人体复杂骨骼及软组织结构。BACKGROUND:At this stage,the biomechanical model of scoliosis patients is too simplified.A complete finite element model of the patient’s trunk bonemuscle has not been established,and the modeling of the mechanical properties of soft tissue is lacking.OBJECTIVE:To establish a real finite element model of the scoliosis trunk with detailed anatomical structure and verify its effectiveness.METHODS:A case of 11-year-old adolescent with scoliosis was selected.The original data in.DICOM format were obtained by 64 slice spiral CT scanning.The finite element model of the trunk was established and its effectiveness was verified.The simulation results of the lumbosacral segment model and the trunk model were compared and verified with the experimental results in the published articles.The implementation of the research scheme meets the relevant ethical requirements of Hebi People’s Hospital(hospital ethical approval No.YK2019015).RESULTS AND CONCLUSION:(1)Model establishment:The finite element model of the whole trunk consisted of more than 8.47 million elements and 1.69 million nodes.(2)Validation of lumbosacral segment model:The average stiffness of the established model under flexion,extension,lateral flexion and torsion was 7.15,2.56,and 1.92 N•m/(°),which was between the experimental results reported in the articles.Load results were consistent with the experimental values in the articles.(3)Verification of the trunk model:Under the action of the three band tensions(20,40,and 60 N),the changes in the stress values of the spine were within the middle value of the experimental results reported in the articles.(4)One constructed adolescent scoliosis trunk biomechanical model with detailed anatomical structure,verified by the validity of the biomechanical model,is reliable,reasonable,true,and intuitive to display the complex bone and soft tissue structure of the human body.

关 键 词：青少年脊柱侧弯 解剖结构 数字化建模 生物力学 有限元分析 

分 类 号：R459.9[医药卫生—治疗学] R496[医药卫生—临床医学]