鼻咽癌放化疗患者癌性厌食现状及影响因素分析  

Cancer-related anorexia in nasopharyngeal carcinoma patients receiving radiotherapy and chemotherapy:the influencing factors

作　　者：张妍欣 杨丽[1] 李家燕 朱静文 邱丽燕 梁秋婷 周溢 叶夏兰 Zhang Yanxin;Yang Li;Li Jiayan;Zhu Jingwen;Qiu Liyan;Liang Qiuting;Zhou Yi;Ye Xialan(Department of Nur-sing,The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)

机构地区：[1]广西医科大学第一附属医院护理部,广西南宁530021

出　　处：《护理学杂志》2021年第21期98-101,共4页Journal of Nursing Science

基　　金：中华护理学会2019年度科研课题(ZHKY201919);2020年广西医科大学第一附属医院自设科研培育项目-护理临床研究攀登计划项目(YYZS2020030)。

摘　　要：目的探讨鼻咽癌放化疗患者癌性厌食现状并分析其影响因素,为实施针对性护理干预提供参考。方法采用癌性厌食量表、症状困扰量表、医院焦虑抑郁量表对200例鼻咽癌放化疗患者进行调查。结果鼻咽癌放化疗患者癌性厌食总分为(20.99±6.70)分,发生率为62.5%;症状困扰条目均分为(6.16±1.29)分,呈中度困扰水平;焦虑、抑郁得分分别为(11.70±3.12)分、(11.18±3.43)分。多元线性回归分析结果显示,患者文化程度、放射性口腔黏膜反应、症状困扰程度、焦虑、抑郁状态是癌性厌食的主要影响因素(P<0.05,P<0.01)。结论医务人员应重视评估鼻咽癌放化疗患者癌性厌食状况,并根据患者癌性厌食状况制订针对性饮食管理策略,改善患者生活质量。Objective To explore the current status of cancer-related anorexia among nasopharyngeal carcinoma patients receiving radiotherapy and chemotherapy,and to probe into its influencing factors.Methods Totally,200 nasopharyngeal carcinoma patients receiving radiotherapy and chemotherapy were surveyed using the Functional Assessment of Anorexia Cachexia Therapy-Anorexia Cachexia Subscale(FAACT-ACS),M.D.Anderson Symptom Inventory-Head&Neck Module,and the Hospital Anxiety and Depression Scale.Results The total score of cancer-related anorexia in nasopharyngeal carcinoma patients receiving chemotherapy and radiotherapy was(20.99±6.70)points,and the incidence rate was 62.5%;the item-level symptom distress score averaged(6.16±1.29)points,being at moderate level;the anxiety and depression scores were respectively(11.70±3.12)and(11.18±3.43)points.The results of multiple linear regression analysis showed that patient′s education level,radiation-induced oral mucositis,symptom distress,anxiety and depression were the main influencing factors of cancer-related anorexia(P<0.05,P<0.01).Conclusion Medical staff should pay attention to cancer-related anorexia in nasopharyngeal cancer patients receiving radiotherapy and chemotherapy,and formulate targeted,effective,and systematic appetite-enhancing intervention strategies,so as to improve the quality of life of patients.

关 键 词：鼻咽癌 放化疗 癌性厌食 症状困扰 焦虑 抑郁 影响因素 

分 类 号：R473.73[医药卫生—护理学]