重庆市某三甲医院医务人员乙肝两对半检测情况分析  

Analysis of Hepatitis B Surface Markers in Medical Staff of a Grade-three General Hospital in Chongqing

作　　者：吴明霞 陈宗涛 WU Mingxia;CHEN Zongtao(Health Management Center,First Affiliated Hospital of Army Medical University,Chongqing 400038,China)

机构地区：[1]陆军军医大学第一附属医院健康管理科,重庆400038

出　　处：《健康体检与管理》2021年第3期197-201,共5页Journal of Health Examination and Management

摘　　要：目的:了解本院医务人员乙肝携带及需要进行乙肝加强免疫的情况。方法:本研究纳入2019年陆军军医大学第一附属医院参加职工体检的所有医务人员,收集其性别、年龄等一般信息,同时对其乙肝相关抗原、抗体滴度、肝功能、肾功能、血常规、血脂、血糖、尿酸、肝脏超声结果等指标进行收集和统计分析。HBsAg检测阳性为乙肝携带组,反之为对照组。结果:本研究共纳入医务人员4611人,其中乙肝携带组113人,阳性率为2.45%,其血浆谷丙转氨酶、谷草转氨酶、碱性磷酸酶浓度较对照组升高(P<0.001),血浆白蛋白、球蛋白浓度较对照组下降(P<0.05)。本次体检医务人员的乙肝两对半结果共出现9种分布情况,其中HBsAg、HBeAg、HBcAb阳性者共7例,占总人数的0.15%,HBsAg、HBeAb、HBcAb阳性者占2.23%,所有指标均阴性者占15.83%。对照组HBsAb阳性的医务人员中,不论性别抗体滴度随年龄增加均逐渐下降(P<0.01)。本次体检中共893人需进行乙肝加强免疫,占此次体检总人数的19.37%,需要注射疫苗的人群主要分布在20~39岁年龄段。结论:本院医务人员HBsAg携带率低于我国平均水平,但需要进行加强免疫比例较高,建议有条件的医疗机构对医务人员开展两对半检测。医务人员应重视平时的乙肝加强免疫工作,医院管理者也应起到监督提醒作用。Objective:To investigate the infection of hepatitis B and the need for strengthen immunity in medical staff.Methods:The study included all medical personnel who participated in staff physical examinations at the first affiliated hospital of The Army medical university in 2019,collected the general information such as gender,age,hepatitis B related markers,liver,kidney function,blood routine,lipid,sugar and uric acid,liver ultrasound results and other indicators.HBsAg positive was the hepatitis B carrier group,whereas the control group.Results:A total of 4611 medical staff werge included in this study,113 of whom were hepatitis B carrier,with a positive rate of 2.45%.The plasma concentrations of alanine aminotransferase,alanine aminotransfer ase and alkaline phosphatase were higher than control group(P<0.001),and the plasma albumin and globulin concentrations were lower than control group(P<0.05).The two-half hepatitis B results showed a total distribution of 9 cases,among which there were 7 HBsAg,HBeAg and HBcAb positive cases,accounting for 0.15%of the total number,HBsAg,HBeAb and HBcAb positive cases accounting for 2.23%,and 15.83%of all indicators were negative.In the control group,antibody titers of both sexes decreased gradually with age(P<0.01).A total of 893 people needed to be immunized against hepatitis b in this physical examination,accounting for 19.37%.The people who needed the vaccine were mainly distributed in 20-39 years old.Conclusion:The HBsAg carrying rate of the medical staff in our hospital is lower than the average level in China,but the proportion of immunization needs to be strengthened is high.Medical staff should attach importance to the routine hepatitis B immunization work,and hospital managers should play the role of supervision and reminder.

关 键 词：医务人员 乙型肝炎 抗体滴度 加强免疫 

分 类 号：R194.3[医药卫生—卫生事业管理]