消化内镜下黏膜切除术治疗食管黏膜下肿瘤的临床疗效探讨  

The Clinical Effect of Digestive Endoscopic Mucosal Resection in the Treatment of Esophageal Submucosal Tumors

作　　者：栾兴龙[1] 苏峰[1] 李园园 程元星 LUAN Xinglong;SU Feng;LI Yuanyuan;CHENG Yuanxing(Department of Gastroenterology,Huxi Hospital,Jining Medical College,Shanxian,Shandong Province,274300 China)

机构地区：[1]济宁医学院附属湖西医院消化内科,山东单县274300

出　　处：《中外医疗》2021年第27期60-63,共4页China & Foreign Medical Treatment

摘　　要：目的探讨食管黏膜下肿瘤治疗中消化内镜下黏膜切除术的临床疗效。方法方便收集2017年9月—2020年9月该院115例食管黏膜下肿瘤患者,随机将其分为观察组(n=65例)与对照组(n=50例),对照组在胸腔镜辅助下行手术治疗,观察组在消化内镜下行黏膜切除术治疗,比较两组患者治疗效果。结果观察组住院时间(4.22±0.74)d与对照组(8.36±2.31)d比较,差异有统计学意义(t=13.587,P<0.05);观察组手术时间(52.46±15.27)min、术中出血量(31.84±10.30)mL明显低于对照组,差异有统计学意义(t=16.758、10.577,P<0.05)。观察组4例患者出现创面渗血,未出现穿孔,并发症发生率为6.15%,对照组有7例患者出血,4例患者穿孔,对照组并发症发生率为22.00%,观察组患者并发症发生率显著低于对照组,差异有统计学意义(χ^(2)=6.257,P<0.05)。观察组患者治疗总有效率93.8%(61/65)显著高于对照组72.0%(36/50),差异有统计学意义(χ^(2)=8.068,P<0.05)。结论食管黏膜下肿瘤患者给予消化内镜下黏膜切除术治疗,具有损伤小、恢复快等优点,是临床值得推广的治疗方式。Objective To investigate the clinical efficacy of digestive endoscopic mucosal resection in the treatment of esophageal submucosal tumors.Methods A total of 115 patients with esophageal submucosal tumors in the hospital from September 2017 to September 2020 were conveniently collected and randomly divided into observation group(n=65 cases)and control group(n=50 cases).The control group was treated with thoracoscopic assisted surgery,and the observation group was treated with digestive endoscopy with mucosal resection.The treatment effects of the two groups were compared.Results The length of stay in the observation group(4.22±0.74)d compared with the control group(8.36±2.31)d,the difference was statistically significant(t=13.587,P<0.05),the operation time(52.46±15.27)min and the intraoperative blood loss(31.84±10.30)mL of the observation group were significantly lower than those of the control group,and the difference was statistically significant(t=16.758,10.577,P<0.05).In the observation group,4 patients had wound bleeding without perforation,and the complication rate was 6.15%,in the control group,7 patients had bleeding and 4 patients had perforation,and the control group had a complication rate of 22.00%,the incidence of complications in the observation group was significantly lower than that in the control group,and the difference was statistically significant(χ^(2)=6.257,P<0.05).The total effective rate of treatment in the observation group was 93.8%(61/65)was significantly higher than 72.0%(36/50)in the control group,the difference was statistically significant(χ^(2)=8.068,P<0.05).Conclusion Patients with submucosal tumors of the esophagus are treated with digestive endoscopic mucosal resection,which has the advantages of less damage and quick recovery,and is a clinical treatment that is worth promoting.

关 键 词：消化内镜下黏膜切除术 食管黏膜下肿瘤 并发症 临床疗效 

分 类 号：R4[医药卫生—临床医学]