外阴部清洁操作对尿液生化指标检测结果的影响  

Effect of vulva cleaning operation to the determination results of urinary biochemical indexes

作　　者：王金铎[1] 崔云卿[1] 张慧 王艳华[1] 李英华[1] WANG Jinduo;CUI Yunqing;ZHANG Hui;LI Yinghua(The Fifth People's Hospital of Shanghai,Fudan University,Shanghai 200240,China)

机构地区：[1]复旦大学附属上海市第五人民医院,上海200240

出　　处：《检验医学》2021年第11期1169-1171,共3页Laboratory Medicine

基　　金：上海市闵行区自然科学基金项目(2017MHZ54,2019MHZ104)。

摘　　要：目的探讨外阴部清洁操作对尿液生化指标检测结果的影响。方法选取35名志愿者,以未清洁外阴部时收集的晨尿样本为未清洗组,以第2天和第3天用0.9%NaCl溶液清洁外阴部后收集的晨尿样本为清洗组。检测尿液微量白蛋白(mAlb)、氯离子(Cl^(-))、肌酐(Cr)、钾离子(K^(+))、钠离子(Na^(+))、总蛋白(TP)、α1-微球蛋白(α1-MG)、β2-微球蛋白(β2-MG)、IgG、转铁蛋白(TF)、钙(Ca)、磷(P)和葡萄糖(Glu)水平,并进行菌落计数及菌种鉴定。结果未清洗组男、女性尿液样本菌落总数差异有统计学意义(P<0.05),mAlb、Cr、IgG、Glu、Ca、P、α1-MG、TF差异均无统计学意义(P>0.05)。清洗组男、女性尿液样本菌落总数、α1-MG、IgG、TF、Cl^(-)、Na^(+)差异均有统计学意义(P<0.05),mAlb、Cr、Glu、Ca、P差异均无统计学意义(P>0.05)。清洗组男性与未清洗组男性尿液样本IgG差异有统计学意义(P<0.05),尿液菌落总数、mAlb、Cr、IgG、Glu、Ca、P、α1-MG、TF差异均无统计学意义(P>0.05)。清洗组女性与未清洗组女性尿液样本各项指标差异均无统计学意义(P>0.05)。结论外阴部清洁操作对男性尿液生化指标检测结果影响较大,但对女性无影响,建议进一步优化女性外阴部清洁操作。Objective To investigate the effect of vulva cleaning operation to the determination results of urinary biochemical indexes.Methods A total of 35 volunteers were enrolled.The morning urine samples collected when the volunteers did not clean the vulva were used as uncleaning group,and the morning urine samples collected after cleaning the vulva with 0.9%NaCl solution on the 2 nd and 3 rd days were used as cleaning group.Urinary microalbumin(mAlb),chloridion(Cl^(-)),creatinine(Cr),kalium ion(K+),sodion(Na^(+)),total protein(TP),alpha1-microglobulin(α1-MG),beta 2-microglobulin(β2-MG),IgG,transferrin(TF),calcium(Ca),phosphorus(P)and glucose(Glu)levels were determined,and colony count determination and bacterial species identification were performed.Results There was statistical significance in total urinary colony count between males and females in uncleaning group(P<0.05),but urinary mAlb,Cr,IgG,Glu,Ca,P,α1-MG and TF had no statistical significance(P>0.05).Between males and females in cleaning group,the total urinary colony count,α1-MG,IgG,TF,Cl-and Na+had statistical significance(P<0.05),and there was no statistical significance in urinary mAlb,Cr,Glu,Ca and P(P>0.05).There was statistical significance in urinary IgG in males between cleaning group and uncleaning group(P<0.05),but there was no statistical significance in total urinary colony count,mAlb,Cr,IgG,Glu,Ca,P,α1-MG and TF(P>0.05).There was no statistical significance for the urinary biochemical indexes between cleaning group and uncleaning group in females(P>0.05).Conclusions The vulva cleaning operation has an impact on the determination results of male urinary biochemical indexes,but there is no impact on the determination results of female.Therefore,the female vulva cleaning operation needs to be further optimized.

关 键 词：生化指标 尿液 外阴部清洁 男性 女性 

分 类 号：R446.1[医药卫生—诊断学]