免疫检查点抑制剂相关性肺炎的中医诊治探索  

TCM Diagnosis and Treatment of Immune Checkpoint Inhibitors Associated with Pneumonia

作　　者：史珍 刘玉霞[2] 蔡成森[2] 邢介锋 王珺[2] SHI Zhen;LIU Yuxia;CAI Chengsen;XING Jiefeng;WANG Jun(Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Respiratory and Critical Care Department,Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250001,China)

机构地区：[1]山东中医药大学,山东省济南市250014 [2]山东中医药大学第二附属医院呼吸与危重症科,山东省济南市250001

出　　处：《实用心脑肺血管病杂志》2021年第11期120-124,共5页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：山东省中医药科技项目(2020M022)。

摘　　要：免疫检查点抑制剂(ICI)治疗肺癌尤其是非小细胞肺癌(NSCLC)及其他实体肿瘤效果明显,但较易引发免疫检查点抑制剂相关性肺炎(CIP),进而增加患者住院天数,加重患者家庭的经济负担。现今临床对CIP的诊治明确,但缺乏个体化的治疗方案,且复发率高。本文结合最新文献报道,从中医病因病机与辨证论治角度对CIP的诊治进行综述,旨在增强医师对CIP的中医认识,以期为临床治疗提供参考。Immune checkpoint inhibitor(ICI) is effective on treating lung cancer, especially non-small cell lung cancer(NSCLC) and the other solid tumors, however, it is easy to cause immune checkpoint inhibitors associated with pneumonia(CIP), which increase hospitalization days and the economic burden of their families. Nowadays, the diagnosis and treatment of CIP is clear, but there is a lack of individualized treatment, and the repetition rate is high. According to the latest literature reports, this paper summarizes the diagnosis and treatment of CIP from the aspects of pathogenesis and syndrome differentiation of traditional Chinese medicine, aiming to enhance doctors’ understanding of CIP, and provide a reference for clinical treatment.

关 键 词：肺炎 免疫检查点抑制剂相关性肺炎 中医诊治 探索 

分 类 号：R563.1[医药卫生—呼吸系统]