低场MRI联合放射影像学检查诊断早期强直性脊柱炎患者骶髂关节病变的效能及对骨代谢指标的影响  

Efficacy of Low-field MRI Combined with Radiographic Examination in the Diagnosis of Early Ankylose Spondylitis Sacroiliac Joint Lesions and Its Influence on Bone Metabolism Indicators

作　　者：胡英 HU Ying(Songzi City Hospital of Traditional Chinese Medicine,Songzi 434200,China)

机构地区：[1]湖北省松滋市中医医院,湖北松滋434200

出　　处：《中国医学创新》2021年第31期129-133,共5页Medical Innovation of China

摘　　要：目的:研究低场MRI联合放射影像学检查诊断早期强直性脊柱炎骶髂关节病变的效能及对骨代谢指标的影响。方法:回顾性分析2015年5月-2020年5月在本院接受治疗检查的80例早期强直性脊柱炎骶髂关节病变患者的临床资料,所有患者均接受低场MRI、CT及X线检查,比较不同检查方式的结果差异并分析早期骨代谢指标。结果:联合检查的检出率均高于X线、CT、低场MRI单独检查,差异均有统计学意义(P<0.05)。0~Ⅳ级单独检查患者关节等级诊出率少于联合检查。X线、CT、低场MRI诊断患者关节等级与联合检查比较,差异均有统计学意义(P<0.05)。不同关节状况患者的腰椎、股骨颈、Word’s三角区、股骨粗隆的骨密度比较,差异均有统计学意义(P<0.05)。不同关节状况患者的BGP、PTH、BALP、CICP、尿DPD、CTX比较,差异均有统计学意义(P<0.05)。随着病变等级的增加,骨密度、BGP、PTH、BALP均降低,CICP、尿DPD、CTX均升高。结论:低场MRI联合放射影像学检查在早期强直性脊柱炎骶髂关节病变中具有重要作用,能有效提升患者病变检出情况,判断早期骨代谢指标,指导临床治疗,具有较高的临床应用价值。Objective:To explore efficacy of low-field MRI combined with radiographic examination in the diagnosis of early ankylose spondylitis sacroiliac joint lesions and its influence on bone metabolism indicators.Method:The clinical data of 80 patients with early ankylose spondylitis sacroiliac joint lesions who received treatment examination in our hospital from May 2015 to May 2020 were retrospectively analyzed.All patients received low-field MRI,CT and X-ray examination,the differences of the results of different examination methods were compared and the early bone metabolism indicators were analyzed.Result:The detection rate of combined examination was higher than that of X-ray,CT and low-field MRI alone,and the differences were statistically significant(P<0.05).The rates of joint grade diagnosis in patients with grade 0-Ⅳalone were less than those in combined examination.There were statistically significant differences in joint grade between patients diagnosed by X-ray,CT and low-field MRI and combined examination(P<0.05).There were significant differences in BMD of lumbar spine,femoral neck,Word’s trigone and femoral trochanter in patients with different joint conditions(P<0.05).There were statistically significant differences in BGP,PTH,BALP,CICP,urinary DPD and CTX in patients with different joint conditions(P<0.05).Bone mineral density,BGP,PTH and BALP were decreased with the increase of lesion grade,while CICP,urinary DPD and CTX were increased with the increase of lesion grade.Conclusion:Lowfield MRI combined with radiographic examination plays an important role in early ankylose spondylitis sacroiliac joint lesions,which can effectively improve the detection of the patient’s lesions,determine early bone metabolism indicators,and guide clinical treatment.It has high clinical application value.

关 键 词：低场MRI 放射影像学检查 早期强直性脊柱炎骶髂关节病变 骨代谢指标 

分 类 号：R593.23[医药卫生—内科学] R445.2[医药卫生—临床医学]