出 处:《中国医学创新》2021年第31期138-142,共5页Medical Innovation of China
基 金:东莞市社会科技发展(一般)项目(202050715001567)。
摘 要:目的:研究超声检测右锁骨下动脉起始部内膜增厚性病变对中青年人群早期动脉硬化的诊断价值。方法:回顾性分析2019年9月-2020年8月于本院体检中心行颈部血管(包括右锁骨下动脉)超声检查的800例中青年的相关资料,依据年龄分为四组,20~29岁为组一(n=190),30~39岁为组二(n=211),40~49岁为组三(n=198),50~59岁为组四(n=201)。所有研究对象超声检测部位包括双侧颈总动脉中远段、颈总动脉分叉处、右锁骨下动脉起始部后壁以及颈内、外动脉起始部,观察比较各组各部位血管内膜中层情况,有无增厚、斑块及斑块结构,管腔有无狭窄及闭塞及血流充盈情况。结果:四组性别构成比较,差异无统计学意义(P>0.05);四组年龄、高血压、糖尿病、吸烟史、饮酒史、脑梗死史、睡眠质量、BMI及TC、TG、LDL、HDL异常情况比较,差异均有统计学意义(P<0.001)。组四以上指标异常均为最多,分别为26例(61.90%)、78例(35.29%)、101例(44.49%)、130例(37.79%)。四组单纯颈动脉内膜增厚62例,占所有研究对象的7.75%,占所有内膜病变的20.20%;单纯锁骨下动脉内膜病变156例,占所有研究对象的19.50%,占所有内膜病变的50.81%;锁骨下及颈动脉均内膜增厚49例,占所有研究对象的6.13%,占所有内膜病变的15.96%;颈动脉、锁骨下动脉存在斑块40例,占所有研究对象的5.00%,占所有内膜病变的13.03%。四组各部位内膜病变情况比较,差异均有统计学意义(P<0.05)。经DSA检测,800例患者中,共有307例动脉硬化患者存在动脉硬化,其中组一、二、三、四分别有6、94、92、115例;同时,超声检查检测各组中存在动脉硬化的患者分别有0、84、91、113例。组一、二、三、四超声检查诊断动脉硬化的灵敏度分别为0、89.36%、95.65%、98.26%,准确率分别为96.84%、95.26%、96.46%、99.00%。结论:不同年龄段的中青年人群的血脂指标存在差异,超声检测右锁骨下动脉起始�Objective:To study the diagnostic value of ultrasound detection of intimal thickening lesions at the beginning of right subclavian artery for early atherosclerosis in young and middle-aged people.Method:The relevant data of 800 middle-aged and young people who underwent ultrasound examination of cervical vessels(including right subclavian artery)in the physical examination center of our hospital from September 2019 to August 2020 were analyzed retrospectively,according to age,the subjects were divided into four groups:group 1(n=190,20-29 years old),group 2(n=211,30-39 years old),group 3(n=198,40-49 years old)and group 4(n=201,50-59 years old).The ultrasonic examination sites of all subjects included the middle and distal segments of bilateral common carotid arteries,the bifurcation of common carotid arteries,the posterior wall of the beginning of right subclavian artery,and the beginning of internal and external carotid arteries,The intima-media,thickening,plaque and plaque structure,lumen stenosis,occlusion and blood flow filling were observed and compared in each group.Result:There was no statistically significant difference in gender composition among four groups(P>0.05).However,there were statistically significant differences in age,hypertension,diabetes,smoking history,drinking history,cerebral infarction history,sleep quality,BMI and TC,TG,LDL and HDL abnormalities among four groups(P<0.001).There were 26 cases(61.90%),78 cases(35.29%),101 cases(44.49%),and 130 cases(37.79%)of TC,TG,LDL and HDL abnormalities in group four,which were the highest among four groups.There were 62 cases of simple carotid artery intimal thickening,accounting for 7.75%of all subjects and 20.20%of all intimal lesions,156 cases of simple subclavian artery intimal lesions,accounting for 19.50%of all subjects and 50.81%of all intimal lesions,49 cases of both subclavian and carotid artery intimal thickening,accounting for 6.13%of all subjects and 15.96%of all intimal lesions,and 40 cases of carotid artery and subclavian artery plaque,a
分 类 号:R543.5[医药卫生—心血管疾病] R445.1[医药卫生—内科学]
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