HFNC治疗间质性肺炎急性加重患者的效果分析  

Effect of HFNC in Patients with Acute Exacerbation of Interstitial Pneumonia

作　　者：段文华[1] DUAN Wenhua(Sanming Second Hospital,Yong’an 366000,China)

机构地区：[1]三明市第二医院,永安市总医院,福建永安366000

出　　处：《中外医学研究》2021年第28期143-145,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨高流量鼻导管氧疗(HFNC)治疗间质性肺炎急性加重患者的效果。方法:选取笔者所在医院2018年1月-2020年1月76例间质性肺炎急性加重患者,按照随机数字表法分为两组,对照组38例,给予无创通气治疗,观察组38例给予HFNC治疗,观察两组临床结局、肺功能及不良事件发生情况。结果:治疗后,观察组使用镇静剂、使用镇痛剂、氧合指数≤200 mmHg及停止口服药>24 h例数均少于对照组(P<0.05);观察组VC及TLC水平均高于对照组(P<0.05);观察组不良事件发生率为7.89%,低于对照组的26.32%(P<0.05)。结论:HFNC治疗间质性肺炎急性加重患者可有效提高肺功能,改善临床结局,同时降低不良事件的发生。Objective:To investigate the effect of high-flow nasal catheter oxygen therapy(HFNC)in the treatment of patients with acute exacerbations of interstitial pneumonia.Method:The 76 patients with acute exacerbation of interstitial pneumonia in our hospital from January 2018 to January 2020 were divided into two groups according to the random number table method.Thirty-eight patients in the control group were treated with non-invasive ventilation,and 38 patients in the observation group were treated with HFNC.The clinical outcome,lung function and occurrence of adverse events between the two groups were observed.Result:After treatment,patients in the observation group who used sedatives,analgesics,oxygenation index≤200 mmHg,and stopped oral medication for more than 24 hours were less than those in the control group(P<0.05);the VC and TLC levels in the observation group were higher than those in the control group(P<0.05).The incidence of adverse events in the observation group was 7.89%,which was lower than 26.32% in the control group(P<0.05).Conclusion:HFNC treatment of acute exacerbation of interstitial pneumonia can effectively improve lung function,improve clinical outcomes,and reduce the occurrence of adverse events.

关 键 词：高流量鼻导管氧疗 间质性肺炎 急性加重期 无创通气 

分 类 号：R563.1[医药卫生—呼吸系统]