中间范围射血分数心力衰竭及其亚组研究进展  

Heart Failure with Mid-Range Ejection Fraction and Its Subgroups

作　　者：于婧 王敬萍[1,2] YU Jing;WANG Jingping(Shanxi Medical University,Taiyuan 030001,Shanxi,China;Department of Cardiology,Shanxi Cardiovascular Hospital,Taiyuan 030024,Shanxi,China)

机构地区：[1]山西医科大学,山西太原030001 [2]山西省心血管病医院心内科,山西太原030024

出　　处：《心血管病学进展》2021年第11期994-997,共4页Advances in Cardiovascular Diseases

基　　金：山西省心血管病医院科研激励计划(XYS20170103)。

摘　　要：2016年ESC急慢性心力衰竭诊断和治疗指南提出新的心力衰竭分型,正式将左室射血分数40%~49%的人群命名为中间范围射血分数心力衰竭。目前针对这一人群的循证医学证据相对不足,对于如何更好地治疗及改善预后仍存在不确定性。此外中间范围射血分数心力衰竭各亚组间具有异质性,使用单一节点的射血分数值确定分类存在一定的局限性,但相关前瞻性研究和临床试验较为匮乏。在整体基础上,更深入地探索与研究各亚组特点,有助于临床医生对中间范围射血分数心力衰竭患者制定针对性的治疗方案。In 2016,the ESC guidelines for the diagnosis and treatment of acute and chronic heart failure has proposed a new classification of heart failure,officially naming people with ejection fraction between 40%and 49%as heart failure with mid-range ejection fraction(HFmrEF).At present,the evidence-based medicine for this population is relatively insufficient,and there is still uncertainty about how to better treat and improve the prognosis.In addition,there is heterogeneity among the subgroups of HFmrEF and the use of the ejection fraction value of a single node to determine the classification has some limits.However,related prospective studies and clinical trials are relatively inadequate.On the overall basis,more profound exploration and research of each subgroup characteristics could help clinicians to formulate targeted treatment plans.

关 键 词：心力衰竭 中间范围射血分数心力衰竭 亚组 异质性 预后 

分 类 号：R541.6[医药卫生—心血管疾病]