防风汤加减联合手法康复对颈椎病血流动力学、血管内皮功能及疗效的影响分析  

Analysis of Influence of Fangfeng Decoction(防风汤)Combined with Rehabilitation on Hemodynamics,Vascular Endothelial Function and Curative Effect in Patients with Cervical Spondylopathy

作　　者：李为敏 王高岸 吴秀香 邱世光 陈香莲 LI Weimin;WANG Gaoan;WU Xiuxiang;QIU Shiguang;CHEN Xianglian(The Second Affiliated Hospital of Hainan Medical College,Haikou 570311,Hainan,China)

机构地区：[1]海南医学院第二附属医院,海南海口570311

出　　处：《中华中医药学刊》2021年第10期247-249,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：海南省卫生计生行业科研项目(18A200131)。

摘　　要：目的探究防风汤加减联合手法康复对颈椎病患者血流动力学、血管内皮功能及疗效的影响分析。方法随机将医院诊治96例颈椎病患者分为对照组和治疗组,两组各48例,对照组给予手法康复治疗,治疗组在对照组的基础上给予防风汤加减,两组疗程均为2周。观察两组患者治疗前后临床疗效、血流动力学、血管内皮功能、视觉模拟评分(VAS)评分、颈椎残障功能量表(NDI)评分及不良反应发生情况。结果治疗后,治疗组总有效率为93.75%(45/48),对照组总有效率为79.17%(38/48),治疗组显著高于对照组(P<0.05);治疗后,两组患者血流动力学指标双侧椎动脉收缩期峰值血流速度(PSV)、舒张期末血流速度(EDV)显著升高(P<0.05),血管阻力指数(RI)、搏动指数(PI)显著降低(P<0.05),治疗组优于对照组(P<0.05);血管内皮功能指标内皮素-1(ET-1)水平较治疗前明显降低(P<0.05),一氧化氮(NO)水平较治疗前升高(P<0.05),治疗组优于对照组(P<0.05);VAS评分、NDI评分均低于治疗前(P<0.05),治疗组低于对照组(P<0.05);两组患者均无明显不良反应,且差异无统计学意义(P>0.05)。结论防风汤加减联合手法康复治疗颈椎病效果显著,可明显患者血流动力学参数及血管内皮功能,无严重不良反应,值得推广应用。e Objective To investigate the effect of Fangfeng Decoction(防风汤)combined with rehabilitation on hemodynam-ics,vascular endothelial function and efficacy in patients with cervical spondylosis.s Methods Ninety-six patients with cervical spondylopathy diagnosed and treated in our hospital were randomly divided into a control group and a treatment group,with 48 cases in each.The control group was given manual rehabilitation treatment,and the treatment group was given Fangfeng Decoc-tion on the basis of the control group.Both courses of treatment were 2 weeks.We observed the clinical efficacy,hemodynamics,vascular endothelial function,visual analogue scale(VAS)score,cervical disability function scale(NDI)score and adverse reac-tions before and after treatment in both groups.s Results After treatment,the total effective rate of the treatment group was 93.75%(45/48),and that of the control group was 79.17%(38/48).The treatment group’s rate was significantly higher than that of the control group(P<0.05).Flow velocity(PSV)and peak diastolic blood flow velocity(EDV)were significantly in-creased(P<0.05),and vascular resistance index(RI)and pulsatility index(PI)were significantly decreased(P<0.05).The treatment group’s indexes were better than those of the control group(P<0.05).The vascular endothelial function index endo-thelin-1(ET-1)level was significantly lower than that before treatment(P<0.05)and the nitric oxide(NO)level was higher than that before treatment(P<0.05).The treatment group’s levels were better than those of the control group(P<0.05).The VAS score and NDI score were lower than those before treatment(P<0.05).The treatment group’s scores were lower than those of the control group(P<0.05).There were no obvious adverse reactions in the two groups and the difference had no statistical significance(P>0.05).n Conclusion The combination of Fangfeng Decoction combined with manipulative rehabilitation in the treatment of cervical spondylopathy is significant.It can show the hemodynamic parameters and v

关 键 词：防风汤 手法康复 颈椎病 血流动力学 血管内皮功能 

分 类 号：R269.815.5[医药卫生—中西医结合]