血液净化与丙种球蛋白治疗儿童重症过敏性紫癜的研究进展  

Progress of blood purification and gamma globulin in the treatment of severe Henoch-Schönlein purpura in children

作　　者：杨星光(综述) 吴玉斌(审校)[1] Yang Xingguang;Wu Yubin(Department of Pediatric Renal Rheumatology and Immunology,Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院小儿肾脏风湿免疫科,沈阳110004

出　　处：《国际儿科学杂志》2021年第10期693-696,共4页International Journal of Pediatrics

摘　　要：过敏性紫癜(Henoch-Schönlein purpura,HSP)是儿童时期常见的小血管炎症,绝大多数预后良好。对于重症HSP,由于患儿体内存在过多的炎症因子,机体损伤持续存在,激素治疗很难在短期内改善症状。近年研究发现丙种球蛋白或血液净化联合激素治疗能更加快速地缓解临床症状,常用的血液净化模式为血浆置换及血液灌流。该文旨在阐述丙种球蛋白及血液净化治疗重症HSP的现状。Henoch-Schönlein purpura(HSP)is a common small vessel inflammation in childhood,and most of them have good prognosis.Due to too many inflammatory factors,the body injury will persist in some severe cases of HSP that hormone alone is difficult to improve symptoms in a short time.Recent studies have found that gamma globulin or blood purification combined with hormone can relieve clinical symptoms more quickly.Plasma exchange and hemoperfusion are commomly used.The purpose of this paper is to review the status of gamma globulin and blood purification treatment in severe HSP.

关 键 词：过敏性紫癜 儿童 丙种球蛋白 血浆置换 血液灌流 

分 类 号：R72[医药卫生—儿科]