The effects of 2-aminoethoxydiphenyl borate and dantrolene on rat bones treated with NaAsO_(2)  

作　　者：Jia Feng Wenjuan Qin Zhen Wang Zijing Zhai Rongji Ma Hailong Lv Yufeng Jiang 

机构地区：[1]Section for Hepatopancreatobiliary Surgery,Department of General Surgery,The Third People’s Hospital of Chengdu,Affiliated Hospital of Southwest Jiaotong University&The Second Affiliated Hospital of Chengdu,Chongqing Medical University,Chengdu 610031,China [2]School of Preclinical Medicine,Chengdu Medical College,Chengdu 610500,China [3]The First Affiliated Hospital,School of Medicine,Shihezi University,Shihezi 832000,China

出　　处：《Acta Biochimica et Biophysica Sinica》2021年第9期1247-1249,共3页生物化学与生物物理学报（英文版）

基　　金：the grant from the School-Level Scientific Research Projects supported by Shihezi University(No.ZZZC202076A).

摘　　要：Heavy metal poisoning is a major public health problem and the main cause of poisoning different systems of the human body[1].However,there are a relatively small number of studies on the effects of arsenic on the trabeculae of Sprague Dawley(SD)rats at present.Therefore,we studied the effects of arsenic on the trabeculae of SD rats and observed the protective effects of 2-aminoethoxydiphenyl borate(2-APB)and dantrolene on the trabeculae of SD rats through establishing an arsenic exposure model and a bone marrow mesenchymal stem cell(BMSC)anti-arsenic cell model,which provided a research basis and a related experimental basis for research on bone injury caused by arsenic,as well as the potential recovery mechanisms.

关 键 词：protective ARSENIC RATS 

分 类 号：Q441[生物学—生理学]