长春西汀治疗急性脑梗死的临床效果和安全性  

Clinical Effect and Safety of Vinpocetine in the Treatment of Acute Cerebral Infarction

作　　者：韩英姬[1] HAN Yingji(Department of Neurology,Yanbian Brain Hospital,Yanji Jilin 133000,China)

机构地区：[1]延边脑科医院神经内科,吉林延吉133000

出　　处：《中国卫生标准管理》2021年第21期82-85,共4页China Health Standard Management

摘　　要：目的分析长春西汀治疗急性脑梗死的临床效果和安全性。方法选取2018年6月—2020年4月医院收治的急性脑梗死患者94例为研究对象,随机摸球法分为对照组47例为常规治疗,观察组47例接受长春西汀治疗,对比两种不同治疗方式下患者神经功能缺损、炎症水平、生存能力和不良反应率。结果治疗前患者神经功能缺损评分差异无统计学意义(P>0.05);治疗后观察组患者神经功能缺损评分低于对照组,差异有统计学意义(P<0.05);治疗前患者炎症因子水平差异无统计学意义(P>0.05);治疗后观察组患者炎症因子水平低于对照组,差异有统计学意义(P<0.05);观察组患者不良反应率和对照组比,差异无统计学意义(P>0.05);治疗前两组患者生存能力评分差异无统计学意义(P>0.05);治疗后观察组患者生存能力评分更高,差异有统计学意义(P<0.05)。结论为急性脑梗死患者予以长春西汀治疗时不仅可改善患者神经功能缺损,提升控制患者炎症水平,提升生存能力,无严重不良反应,有应用价值。Objective To analyze the clinical effect and safety of vinpocetine in the treatment of acute cerebral infarction.Methods 94 patients with acute cerebral infarction in our hospital from June 2018 to April 2020 were selected as the research objects.They were divided into the control group 47 cases as conventional treatment,47 cases in the observation group received vinpocetine treatment according to randomly touching ball method,and compared the neurological deficit,inflammation level,survival ability and adverse reaction rate of the patients under the two different treatment methods.Results There was no significant difference in neurological deficit score before treatment(P>0.05);after treatment,neurological deficit score of observation group was lower than that of control group,the difference was statistically significant(P<0.05);there was no significant difference in inflammatory factor level of patients before treatment(P>0.05);after treatment,inflammatory factor level of observation group was lower than that of control group,the difference was statistically significant(P<0.05).There was no significant difference in the adverse reaction rate between the observation group and the control group(P>0.05);there was no significant difference in the score of quality of life between the two groups before treatment(P>0.05);the score of quality of life in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).Conclusion Vinpocetine for patients with acute cerebral infarction can not only improve the neurological deficit,improve the control of inflammation level,improve the quality of life,no serious adverse reactions,has application value.

关 键 词：长春西汀 急性脑梗死 神经功能缺损 全血黏度 纤维蛋白 炎症因子 

分 类 号：R287[医药卫生—中药学]