杜松烷型倍半萜及其药理活性研究进展  

Progress in the studies of the Cadinane-type sesquiterpenoids and their pharmacological activities

作　　者：梁旭 杨新洲[2] 江姗 邓巧玉 陈兴广 贾学恭 邓富声 袁经权[1] LIANG Xu;YANG Xin-zhou;JIANG Shan;DENG Qiao-yu;CHEN Xing-guang;JIA Xue-gong;DENG Fu-sheng;YUAN Jing-quan(Scientific Experimental Center of Guangxi University of Chinese Medicine,Nanning 530200,China;South-Central University for Nationalities,Wuhan 430074,China)

机构地区：[1]广西中医药大学科学实验中心,广西南宁530200 [2]中南民族大学药学院,湖北武汉430074

出　　处：《中草药》2021年第19期6121-6134,共14页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(81660656)。

摘　　要：杜松烷型的倍半萜在自然界中种类繁多、分布广泛、结构复杂,是植物精油重要组成成分。该类型的化合物中部分具有较好的抗炎、抗菌、抗肿瘤、抗疟疾等药理作用。主要对近10年来杜松烷型倍半萜的最新结构和药理活性研究进展进行分类和总结,以期为杜松烷型倍半萜类成分的研究和开发提供参考。Cadinane-type sesquiterpenoids, the important components of essential oils, are abundant and widely distributed in nature. Some of these compounds have better anti-inflammatory, anti-bacterial, anti-neoplastic, anti-malarial and other pharmacological activities. In this paper, the latest structures and pharmacological activities of cadinane-type sesquiterpenoids in recent ten years were reviewed in order to provide reference for further research and development of these components.

关 键 词：杜松烷型倍半萜 化学成分 药理作用 抗疟疾 抗炎 抗菌 抗肿瘤 

分 类 号：R28[医药卫生—中药学]