气相色谱-质谱法测定食品接触材料中2-甲基-1,3-丙二醇和新戊二醇的迁移量  

Determination of Migration of 2-Methyl-1,3-Propanediol and 2,2-Methyl-1,3-Propanediol in Food Contact Materials by Gas Chromatography-Mass Spectrometry

作　　者：贝荣华 陈湘颖 董犇 钟怀宁 陈燕芬 曾莹 陈胜 李丹 蔡汶静 郑建国 BEI Rong-hua;CHEN Xiang-ying;DONG Ben;ZHONG Huai-ning;CHEN Yan-fen;ZENG Ying;CHEN Sheng;LI Dan;CAI Wen-jing;ZHENG Jian-guo(Guangzhou Customs Technical Center,Guangzhou 510665,China)

机构地区：[1]广州海关技术中心,广东广州510665

出　　处：《分析测试学报》2021年第11期1657-1662,共6页Journal of Instrumental Analysis

基　　金：国家重点研发计划项目(2016YFF0203705);广州海关科研项目(2021GZCK12,2020GZCK-026)。

摘　　要：建立了食品接触材料中2-甲基-1,3-丙二醇(MPO)和新戊二醇(NPG)迁移量的气相色谱-质谱(GCMS)检测方法。食品接触材料经迁移试验后,所得浸泡液经苯硼酸溶液衍生化、正己烷萃取后,GC-MS测定。结果表明,该方法在优化条件下的线性相关性良好,相关系数(r^(2))大于0.995;MPO和NPG在4%乙酸、10%乙醇、50%乙醇和异辛烷中的检出限均为0.01 mg/L;线性范围均为0.02~0.10 mg/L;在95%乙醇中,MPO的检出限为0.30 mg/L,线性范围为0.50~1.6 mg/L,NPG的检出限为0.03 mg/L,线性范围为0.05~0.16 mg/L。该方法在低、中、高3个浓度水平的平均回收率为85.0%~112%,相对标准偏差(RSD)为0.60%~9.5%。该方法的检测结果准确、灵敏度高,能较好地实现食品接触材料及制品中MPO和NPG迁移量的测定,满足我国法规的限量要求。A gas chromatography-mass spectrometry(GC-MS)was developed for the determination of migration of 2-methyl-1,3-propanediol(MPO)and 2,2-methyl-1,3-propanediol(NPG)in food contact materials. After the migration test of food contact materials,the obtained soaking solution was firstly derivatized with phenylboric acid solution, then extracted with n-hexane, and finally determined by GC-MS. Results showed that there were good linear relationship of this method in the optimized conditions,with correlation coefficients(r^(2))larger than 0. 995. The detection limits for MPO and NPG in 4%acetic acid, 10%ethanol, 50%ethanol and isooctane were all 0. 01 mg/L within linear ranges of 0. 02-0. 10 mg/L. The detection limit of MPO in 95%ethanol was 0. 30 mg/L within a linear range of 0. 50-1. 6 mg/L. The detection limit for NPG in 95%ethanol was 0. 03 mg/L within a linear range of 0. 05-0. 16 mg/L. The relative standard deviations(RSD)of this method were in the range of 0. 60%-9. 5%,and the average recoveries were 85. 0%-112%. With the high accuracy and sensitivity,the method could be used to determine the migration of 2-methyl-1,3-propanediol and 2,2-methyl-1,3-propanediol in food contact coatings and plastic products, so as to meet the limited requirements of Chinese regulations.

关 键 词：2-甲基-1 3-丙二醇(MPO) 新戊二醇(NPG) 食品接触材料 气相色谱-质谱法(GC-MS) 衍生化法 

分 类 号：O657.71[理学—分析化学] O622.3[理学—化学]