苯甲酰脲类杀虫剂研究进展  

Research Progress of Benzoylurea Insecticides

作　　者：王燕燕[1] Wang Yanyan(Patent Examination Cooperation Jiangsu Center of the Patent Office,CNIPA,Suzhou 215163,China)

机构地区：[1]国家知识产权局专利局专利审查协作江苏中心,江苏苏州215163

出　　处：《广东化工》2021年第19期102-103,共2页Guangdong Chemical Industry

摘　　要：苯甲酰脲类杀虫剂以昆虫表皮为靶标,具有靶向性强的特点。本文选取了中文数据库CNABS、外文数据库VEN,采用关键词、分类号、STN结合的方式,对该类杀虫剂的专利情况进行了检索,检索时间截止到2021年5月15日。现有技术多运用生物电子等排原理、拼接原理等,进行取代基取代、苯环杂环替换,将药效基团引入初始化合物,并进行药物活性测定。尝试活性基团的结构拼接是未来进一步的发展方向。Benzoyl urea pesticides target insect cuticle and have strong targeting ability.This paper selected the Chinese database CNABS,foreign language database VEN,using keywords,classification number and STN to retrieval.The retrieval time is up to May 15,2021.Most of the existing technologies use the principle of bioisosterism or splicing to replace substituents or replace phenyl with heterocyclic rings,introduce the pharmacophore into the initial compound,and determine the drug activity.The structure splicing of other active groups and adjusting the catalysts maybe the further development direction.

关 键 词：苯甲酰脲 杀虫剂 专利 几丁质抑制剂 电子等排 

分 类 号：TQ[化学工程]