支气管肺泡灌洗指南的方法学质量评价  

Clinical practice guidelines of bronchoalveolar lavage:a methodological quality study

作　　者：李万怡 王永军[1,2] 魏莉莉 杨柳[1,2,6] 王文媛 张瑞鹏 杜威萍[8] 杨克虎 刘东海 易彬 LI Wanyi;WANG Yongjun;WEI Lili;YANG Liu;WANG Wenyuan;ZHANG Ruipeng;DU Weiping;YANG Kehu;LIU Donghai;YI Bin(Department of Pediatric Respiratory Medicine,Gansu Provincial Maternity and Child-care Hospital,Lanzhou 730050,P.R.China;Pediatric Clinical Medicine Research Center of Gansu Province,Lanzhou 730050,P.R.China;Evidence-based Medicine Center of Lanzhou University,Lanzhou 730000,P.R.China;Key Laboratory of Evidence-based Medicine and Clinical Transformation of Gansu Province,Lanzhou 730000,P.R.China;Industry Technology Centre for Medical Guideline of Gansu Province,Lanzhou 730000,P.R.China;School of Nursing,Lanzhou University,Lanzhou 730000,P.R.China;School of Nursing,Gansu University of Traditional Chinese Medicine,Lanzhou 730000,P.R.China;Wuwei People’s Hospital,Wuwei 733000,P.R.China)

机构地区：[1]甘肃省妇幼保健院小儿呼吸科,兰州730050 [2]甘肃省儿科临床医学研究中心,兰州730050 [3]兰州大学基础医学院循证医学中心,兰州730000 [4]甘肃省循证医学与临床转化重点实验室,兰州730000 [5]甘肃省医学指南行业技术中心,兰州730000 [6]兰州大学护理学院,兰州730000 [7]甘肃省中医药大学护理学院,兰州730000 [8]武威市人民医院,甘肃武威733000

出　　处：《中国循证医学杂志》2021年第11期1325-1331,共7页Chinese Journal of Evidence-based Medicine

基　　金：甘肃省自然科学基金项目(编号:1606RJZA175);甘肃省循证医学与临床转化重点实验室“开放课题”资助(编号:GSEBMKT-2021KFKT01)。

摘　　要：目的系统评价支气管镜肺泡灌洗指南的方法学质量。方法计算机检索CNKI、VIP、WanFang Data、CBM、Web of Science、PubMed、EMbase数据库及医脉通、美国国立指南文库(NGC)、国际指南协作网(GIN)、苏格兰校际指南网络(SIGN)、英国国家临床优化研究所(NICE)、世界卫生组织(WHO)网站,搜集支气管肺泡灌洗的相关指南,检索时限均从建库至2020年12月。由4名研究员独立筛选文献、提取资料后,采用指南研究与评价(AGREEⅡ)工具对纳入指南的方法学质量进行评价。结果最终纳入19部指南,包括中国5部、美国5部、欧洲3部、英国2部、澳大利亚1部、以色列1部、西班牙1部、印度1部。19部指南在范围和目的、参与人员、制订严谨性、清晰性、应用性和独立性6个领域的平均标化得分率为50.73%、20.02%、15.13%、36.40%、3.51%和22.37%。结论目前国内外支气管肺泡灌洗相关指南质量相对较低。Objective To assess the methodological quality of guidelines for bronchoscopic alveolar lavage.Methods CNKI,VIP,WanFang Data,CBM,Web of Science,PubMed,EMbase databases and medlive.cn,the National Guideline Clearinghouse(NGC),the National Guideline International Network(GIN),the Scottish Intercollegiate Guidelines Network(SIGN),the National Institute for Clinical Excellence(NICE),and the World Health Organization(WHO)websites were electronically searched to collect guidelines of bronchoscopic alveolar lavage from inception to December 2020.Two reviewers independently screened literature,extracted data,and assessed the methodological quality of the guidelines by using AGREEⅡtool.Results A total of 19 guidelines were included,with 5 from China,5 from the USA,3 from Europe,2 from the UK,1 from Australia,1 from Israel,1 from Spain,and 1 from India.The average standard score rates of the 19 guidelines in the six fields were 50.73%for scope and purpose,20.02%for participants,15.13%for formulation rigor,36.40%for clarity of presentation,3.51%for applicability,and 22.37%for editorial independence.Conclusions The quality of bronchoalveolar lavage guidelines remains relatively low.

关 键 词：支气管镜 肺泡灌洗 指南 质量评价 AGREEⅡ 

分 类 号：R562.2[医药卫生—呼吸系统] R-03[医药卫生—内科学]