肾脏不同细胞间对话在糖尿病肾脏疾病中的研究进展  

Research advances in crosstalk between kidney cells in diabetic kidney disease

作　　者：高林 杨炎林 孙崇凯 薛耀明[2] GAO Lin;YANG Yanlin;SUN Chongkai(The First Clinical Medical Institute,Southern Medical University,Guangzhou 510515,China)

机构地区：[1]南方医科大学第一临床医学院,广州510515 [2]南方医科大学南方医院内分泌代谢病科

出　　处：《中国糖尿病杂志》2021年第11期867-870,共4页Chinese Journal of Diabetes

摘　　要：DKD是导致终末期肾脏病的重要原因。肾脏不同细胞间存在广泛的对话关系,尤以肾小球内皮细胞、足细胞及肾小管上皮细胞间的对话机制研究最广泛。研究不同细胞间对话可进一步探讨DKD发病机制。本文对肾脏不同细胞间对话在DKD中的研究进展进行综述。Diabetic kidney disease(DKD)is an important cause of end-stage renal disease. There is an extensivecrosstalkamong renal cells. Lots of studies focus on the mechanism of crosstalk between glomerular endothelial cells,podocytes,andrenal tubular epithelial cells. Researches ofthe crosstalkbetween different cells could help understandingthe pathogenesis of DKD. This article reviews the progress of renal intercellular communication in DKD.

关 键 词：糖尿病肾脏疾病 细胞对话 肾小球细胞 肾小管细胞 

分 类 号：R587.2[医药卫生—内分泌] R692.9[医药卫生—内科学]