不同运动干预方式对老年人肌少症改善效果的Meta分析  

Effect of Different Modes of Exercise on Sarcopenia in Older Adults:A Meta-analysis

作　　者：温鹏天 张瑞丽[1] 胡文清[2] 王娴 吴景梅[1] 李慧娟[1] WEN Peng-tian;ZHANG Rui-li;HU Wen-qing;WANG Xian;WU Jing-mei;LI Hui-juan(Department of Nursing Teaching,the Fourth Hospital of Hebei Medical University,Shijiazhuang,Hebei 050011,China;Department of Rehabilitation,the Third Hospital of Hebei Medical University,Shijiazhuang,Hebei 050011,China)

机构地区：[1]河北医科大学第四医院护理教学办公室,河北石家庄市050011 [2]河北医科大学第三医院康复医学科,河北石家庄市050011

出　　处：《中国康复理论与实践》2021年第11期1291-1298,共8页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的评价单一和多种运动干预对老年人肌少症的改善效果。方法计算机检索PubMed、Embase、Web of Science、Cochrane Library、中国知网、维普和万方7个数据库,收集从建库至2021年7月发表的关于探讨单一与多种运动对老年人肌少症改善效果的随机对照研究。由两名研究人员进行文献检索与筛选,并独立对纳入文献进行质量评价。采用RevMan 5.3软件进行Meta分析。结果最终纳入15篇文献,共816例患者。与空白对照组相比,单一运动(MD=-0.05,95%CI-0.14~0.04,P>0.05)和多种运动(MD=0.15,95%CI-0.01~0.31,P>0.05)对骨骼肌质量指数的效果不显著;单一运动(MD=2.06,95%CI 0.25~3.87,P<0.05)和多种运动(MD=2.36,95%CI 1.10~3.63,P<0.001)能改善最大握力;多种运动能显著改善膝关节伸展肌力(SMD=0.49,95%CI 0.26~0.73,P<0.001)和步速(SMD=0.24,95%CI 0.19~0.29,P<0.001)。结论单一运动能改善肌少症老年人的最大握力,多种运动能改善最大握力、膝关节伸展肌力和步速。Objective To evaluate the effectiveness of single modal and multimodal exercise interventions on sarcopenia in the elderly.Methods Randomized controlled trials about the effects of single modal and multimodal exercises on the improvement of sarcopenia in the elderly were retrieved from seven databases(PubMed,Embase,Web of Science,Cochrane Library,CNKI,VIP and Wanfang data)from the establishment of the databases to July,2021.Two researchers selected the literatures independently,and evaluated the quality of methodology.The meta-analysis was performed with RevMan 5.3.Results A total of 15 studies were incorporated,including 816 cases of sarcopenia.Compared to the blank control group,the skeletal muscle mass index improved little with single(MD=-0.05,95%CI-0.14 to 0.04,P>0.05)and multiple(MD=0.15,95%CI-0.01 to 0.31,P>0.05)exercises.The maximum grip force improved with both single(MD=2.06,95%CI 0.25 to 3.87,P<0.05)and multiple(MD=2.36,95%CI 1.10 to 3.63,P<0.001)exercises.The knee extensors strength(SMD=0.49,95%CI 0.26 to 0.73,P<0.001)and the walking speed(MD=0.24,95%CI 0.19 to 0.29,P<0.001)improved with multimodal exercises.Conclusion Single modal exercise may improve maximal grip strength in the elderly with sarcopenia,and multimodal exercise may be effective on maximal grip strength,knee extensors strength and walking speed.

关 键 词：肌少症 老年 运动 META分析 

分 类 号：R685.5[医药卫生—骨科学]