离子色谱—三重四级杆质谱联用法快速测定水中丁基黄原酸  

Rapid Determination of Butyl Xanthate in Water by Ion Chromatography-Triple Quadrupole Mass Spectrometry

作　　者：张秀尧[1] 蔡欣欣[1] 张晓艺[1] 李瑞芬[1] ZHANG Xiuyao;CAI Xinxin;ZHANG Xiaoyi;LI Ruifen

机构地区：[1]温州市疾病预防控制中心

出　　处：《环境卫生学杂志》2021年第3期275-279,共5页JOURNAL OF ENVIRONMENTAL HYGIENE

摘　　要：目的建立快速检测水中丁基黄原酸的离子色谱—三重四极杆质谱联用分析方法。方法水样经0.22μm滤膜过滤后直接进样,以IonPac AS 19型阴离子交换色谱柱(2 mm×250 mm,7.5μm)作为分离柱,自动在线产生的氢氧化钾进行梯度分离,色谱柱流出液经阴离子抑制器抑制后进入质谱系统,以电喷雾电离负离子多离子监测模式(MRM)进行检测,内标法定量。结果方法的线性范围为(0.7~500)μg/L,自来水和河水中丁基黄原酸的平均加标回收率为95.6%~107.1%,相对标准偏差为3.1%~11.2%(n=6),方法的检出限为0.2μg/L。结论本法操作简单、灵敏度高、准确性好,适合于水中丁基黄原酸的测定,已应用于实际样品的测定。Objective To establish a method for rapid determination of butyl xanthate in water based on ion chromatography-triple quadrupole mass spectrometry.Methods Water samples were filtered through 0.22μm filter membrane before analysis,and separation of butyl xanthate was performed on a Dionex IonPac AS 19 column(2 mm×250 mm,7.5μm),with the electrolytically generated eluent potassium hydroxide for gradient elution.An on-line suppressor was used to remove potassium ion from the eluent and then the eluent flow entered the mass spectrometer.A triple quadrupole mass spectrometer,equipped with electrospray ionization(ESI)in the negative ion mode,was used to measure butyl xanthate in the multiple reaction monitoring(MRM)mode,and the internal standard method was used for determination.Results The linear range was(0.7-500)μg/L.The average recovery of butyl xanthate in tap water and river water ranged from 95.6%to 107.1%,with a relative standard deviation of 3.1%-11.2%(n=6).The limit of detection of this method was 0.2μg/L.Conclusion The method is simple,sensitive,and accurate,and is suitable for the determination of butyl xanthate in water.It has been successfully applied to the determination of butyl xanthate in water sample.

关 键 词：离子色谱—三重四极杆质谱联用法 丁基黄原酸 水 

分 类 号：R12[医药卫生—环境卫生学]