临床药师在呼吸系统疾病患儿抗生素合理应用中的作用  

Role of clinical pharmacists in rational use of antibiotics in children with respiratory diseases

作　　者：弋佩玉 闻浩 YI Peiyu;WEN Hao(Children’s Hospital Affiliated to Zhengzhou University,Henan Children’s Hospital,Zhengzhou Children’s Hospital,Zhengzhou 450000 Henan,China)

机构地区：[1]郑州大学附属儿童医院河南省儿童医院郑州儿童医院,河南郑州450000

出　　处：《中国民康医学》2021年第21期129-131,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察临床药师在呼吸系统疾病患儿抗生素合理应用中的作用。方法:选取82例呼吸系统疾病患儿为研究对象,采用随机数字表法分为对照组和观察组各41例。对照组采用临床医师经验用药方案,观察组采用有临床药师参与的抗生素用药方案,比较两组抗生素使用情况[抗生素使用率、抗生素品种选择及用量合理率、单一及联合用药率]、不良反应发生率、住院时间和医疗费用。结果:两组抗生素使用率和用量规范率比较,差异均无统计学意义(P>0.05);观察组抗生素选择合理率和单一用药率高于对照组,二联用药率、三联用药率低于对照组,差异均有统计学意义(P<0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05);观察组住院时间短于对照组,医疗费用少于对照组,差异均有统计学意义(P<0.05)。结论:有临床药师参与的呼吸系统疾病患儿抗生素用药方案,可提高抗生素选择合理率和单一用药率,降低联用率和不良反应发生率,缩短住院时间,以及减少医疗费用,效果优于临床医师经验用药方案。Objective:To analyze Role of clinical pharmacists in rational use of antibiotics in children with respiratory diseases.Methods:82 children with respiratory diseases were selected as the research objects,and were divided into control group and observation group by using the random number table method,41 cases in each group.The control group adopted the clinicians’experience medication plan,while the observation group was given the antibiotic medication plan with the participation of the clinical pharmacists.The antibiotic use[antibiotic use rate,antibiotic reasonable selection rate,dosage standard rate,single and multiple antibiotic use rate],the incidence of adverse reactions,the hospitalization time,and the medical expenses were compared between the two groups.Results:There were no statistically significant difference between the two groups in the antibiotic use rate and the dosage standard rate(P>0.05).The antibiotics rational selection rate and the single antibiotic use rate in the observation group were higher than those in the control group;the combined use rate of two antibiotics and the combined use rate of three antibiotics were lower than those in the control group;and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Further,the hospitalization time in the observation group was shorter than that of the control group;the medical expenses were less than that of the control group;and the differences were statistically significant(P<0.05).Conclusions:The antibiotic medication plan for the children with respiratory diseases with the participation of the clinical pharmacists can increase the antibiotic reasonable selection rate,dosage standard rate and the single antibiotic use rate,reduce the combined rate of two antibiotics and combined use rate of three antibiotics,and the incidence of adverse reactions,and shorten the hospitalization time,and

关 键 词：临床药师 呼吸系统疾病 儿科 抗生素合理应用 

分 类 号：R95[医药卫生—药学]