腹腔镜下全子宫切除术后口服香芍颗粒对围绝经期症状及卵巢功能的影响  

Effect of oral Administration of Xiangshao granules after Laparoscopic hysterectomy on Perimenopausal Symptoms and ovarian function

作　　者：茆志洁 Mao Zhijie(Department of Gynecology,Wujin Hospital affiliated to Jiangsu University/Wujin Clinical College,Xuzhou Medical University,Changzhou 213000,China)

机构地区：[1]江苏大学附属武进医院/徐州医科大学武进临床学院妇科,江苏常州213000

出　　处：《实用妇科内分泌电子杂志》2021年第11期57-60,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨腹腔镜下全子宫切除术后口服香芍颗粒对围绝经期症状及卵巢功能的影响。方法选取82例行腹腔镜下全子宫切除术患者,按入院先后顺序将其分为对照组与研究组,每组41例。对照组术后采用雌激素治疗,研究组术后采用香芍颗粒治疗。对比两组患者治疗前后血清性激素水平、卵巢体积、Kupperman绝经指数(KMI)评分及临床疗效。结果治疗前,两组患者雌二醇(E_(2))、促黄体生成素(LH)及卵泡刺激素(FSH)水平对比,差异无统计学意义(P>0.05);治疗3个月后,两组患者LH、FSH激素水平均显著高于治疗前,E?水平显著低于治疗前,且研究组患者LH、FSH/K平均低于对照组,E_(2)水平高于对照组,差异均具有统计学意义(P<0.05)。两组患者治疗前、治疗3个月后卵巢体积对比差异无统计学意义(P>0.05)。治疗3个月后,研究组患者KMI评分为(6.4±2.5)分,对照组患者KMI评分为(7.7±2.8)分,研究组患者KMI评分显著低于对照组,差异具有统计学意义(P<0.05)。研究组患者治疗总有效率为90.24%,明显高于对照组的70.73%,差异具有统计学意义(P<0.05)。结论腹腔镜下全子宫切除术后患者采用香芍颗粒治疗可改善围绝经期症状,改善卵巢功能,具有临床应用价值。Objective To investigate the efiects of Xiangshao granules after laparoscopic hysterectomy on perimenopausal symptoms and ovarian function.Methods 82 patients undergoing laparoscopic hysterectomy were divided into control group and study group according to the order of admission,41 cases in each group.The control group was treated with estrogen,and the research group was treated with Xiangshao granules.Serum sex hormone levels,ovarian volume,Kuppennan menopause index(KMI)score and clinical efficacy were compared between the two groups before and after treatment.Results Before treatment,there were no significant differences in the levels of estradiol(E_(2)),luteinizing hormone(LH)and follicle stimulating hormone(FSH)between 2 groups(P>0.05).After 3 months of treatment,the LH and FSH hormone levels in 2 groups were significantly higher than before,and the E_(2) level was significantly lower than before,and the LH and FSH levels in study group were lower than control group,and the E_(2) level was higher than control group,the differences were statistically significant(P<0.05).There was no significant difierence in ovarian volume between 2 groups before and 3 months after treatment(P>0.05).After 3 months of treatment,the KMI score of the study group was(6.4±2.5)and that of the control group was(7.7±2.8).The KMI score of the study group was significantly lower than that of the control group,the difference was statistically significant(P<0.05).The total eflfective rate of the study group was 90.24%,which was significantly higher than that of the control group(70.73%),the difference was statistically significant(P<0.05).Conclusion The treatment of xiangshao granules after laparoscopic hysterectomy can improve perimenopausal symptoms and ovarian function,which has clinical application value.

关 键 词：香芍颗粒 围绝经期症状 卵巢功能 

分 类 号：R713.4[医药卫生—妇产科学]