椎动脉开口支架术后再狭窄的危险因素研究  

A Study on the risk factors of restenosis after stenting of vertebral artery ostium

作　　者：刘西银 李雪雁 卜祎 LIU Xiyin;LI Xueyan;BO Yi(Cardiovascular and Cerebrovascular Disease Hospital,General Hospital of Ningxia Medical University,Yinchuan 750002,China;Department of Neurology,the First People's Hospital of Yinchuan,Yinchuan 750004,China;Department of Neurology,General Hospital of Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学总医院心脑血管病医院肾脏内科,宁夏银川750002 [2]宁夏银川市第一人民医院神经内科,宁夏银川750001 [3]宁夏医科大学总医院神经内科,宁夏银川750004

出　　处：《宁夏医学杂志》2021年第11期986-988,共3页Ningxia Medical Journal

基　　金：宁夏医科大学校级科研项目(XM2018155)。

摘　　要：目的通过对椎动脉开口支架植入术后再狭窄的危险因素分析,为临床支架选择以及术后再狭窄的预防提供参考。方法对椎动脉支架术患者174例术后6个月进行随访,通过收集患者临床资料及影像学资料,分为再狭窄组(27例)与非狭窄组(147例),比较2组患者支架直径、支架长度、植入侧别、支架类型(金属或药物洗脱支架)、血管迂曲或钙化等指标,并采用单因素及多因素Logistic回归分析椎动脉开口支架术后再狭窄的危险因素。结果单因素及多因素Logistic回归分析显示,血管钙化、血管迂曲、支架直径≤3.5 mm、金属支架均是椎动脉开口支架植入术后支架内再狭窄的独立危险因素(P<0.05)。结论血管钙化、血管迂曲、支架直径≤3.5 mm是椎动脉支架术后再狭窄的危险因素,药物洗脱支架可明显降低术后的再狭窄率。Objective To analysis the risk factors of restenosis after vertebral artery opening stent implantation,and to provide reference for the selection of clinical stents and the prevention of postoperative restenosis.Methods A total of 174 patients underwent vertebral artery stenting in our hospital were followed up 6 months after surgery.According to the clinical data and imaging data,patients were divided into restenosis group(27 cases)and non-stenosis group(147 cases).Stent diameter,stent length,implantation side,stent type(metal or drug-eluting stent),vascular entanglement or calcification were compared.Univariate and multivariate logistic regression were used to analyze the risk factors of restenosis after vertebral artery opening stent stenting.Results Univariate and multivariate logistic regression analysis showed that vascular calcification,vascular tortuosity,stent diameter≤3.5 mm,and metal stent were all independent risk factors for in-stent restenosis after vertebral artery opening stent implantation(P<0.05).Conclusion Vascular calcification,vascular tortuosity and stent diameter≤3.5 mm are the risk factors for restenosis after vertebral artery stenting.Drug-eluting stents can significantly reduce the restenosis rate after vertebral artery stenting.

关 键 词：椎动脉开口狭窄 术后支架内再狭窄 危险因素 支架类型 

分 类 号：R543.5[医药卫生—心血管疾病]